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NEWS Jun 30 2013

The TALE of New Tools to Study Gene Regulation

In nearly every organism’s genome, scattered between genes that encode proteins, long regulatory regions stretch across expanses of DNA. Understanding what role these so-called enhancer regions...

NEWS Sep 8 2010

Scientists Discover Gene Mutation Common in a Class of Ovarian Cancers

A study of aggressive ovarian tumors has revealed a new class of major cancer-driving mutations. Howard Hughes Medical Institute (HHMI) researchers found that most of the clear cell ovarian carcinoma...

NEWS Jan 16 2017

New Tools Will Drive Greater Understanding of Wheat Genes

Howard Hughes Medical Institute scientists have developed a much-needed genetic resource that will greatly accelerate the study of gene functions in wheat. The resource, a collection of wheat seeds...

NEWS Feb 22 2016

Clock Gene May Connect Mood and Sleep

If you pull an all-nighter or stay up late to binge-watch Game of Thrones, you will probably be grumpy the next day. But if you don’t get enough sleep for weeks or months on end, you may...

NEWS Feb 26 2015

Left or Right? The Brain Knows Before You Move

With half a second's planning, an animal’s brain prepares it to quickly and precisely execute complex movements. Scientists at Howard Hughes Medical Institute's Janelia Research Campus have...

NEWS Nov 2 2016

How the African Striped Mouse Got Its Stripes

A gene called Alx3 blocks the differentiation of pigment-producing cells in the skin of the African striped mouse, thus generating the mouse’s characteristic light-colored stripes, a new...

NEWS Sep 28 2017

New Role for Fragile X Protein Could Offer Clues for Treatment

The protein behind fragile X syndrome acts as a genetic conductor, orchestrating a symphony of genes that help shape DNA’s 3-D structure. Fragile X mental retardation protein, or FMRP, oversees a...

BULLETIN ARTICLE May 1 2012

Locating a Genetic Glitch

A team of 41 scientists led by HHMI investigator Louis Ptáček has pinpointed the gene responsible for a rare disease that causes sudden, uncontrollable movements. The culprit is a little known...

OTHER

Blazing a Genetic Trail

“Blazing a Genetic Trail,” originally published in 1991, was the second in a series of reports about biomedical science. We have removed this content from our website because the information was...

NEWS Apr 8 2005

Genetic Tool Reaps Rich Harvest

In one fell swoop, scientists have increased from dozens to hundreds the number of known genes that control crucial steps in the development of many organisms from fruit flies to humans. Using the...

NEWS Jul 28 2011

Genetics of Head and Neck Cancers Discovered

Two independent studies by teams of Howard Hughes Medical Institute (HHMI) scientists have revealed genetic mutations often present in the most common form of head and neck cancer—squamous...

NEWS Feb 17 2011

Speedy Genetics Reveals Stem Cell Twists

As the body’s source of a variety of cell types, stem cells must split their energy between creating copies of themselves to ensure a steady supply, and crafting new cells specialized for...

NEWS Oct 12 2017

Whole Genome Sequencing Identifies New Genetic Signature for Autism

Autism has genetic roots, but most cases can’t be explained by current genetic tests. Now, patterns found in autistic children’s genomes – the complete set of genetic instructions inside cells –...

NEWS Nov 2 2016

Mouse Mutants May Shed Light on the Mysteries of Sleep

The first unbiased genetic screen for sleep defects in mice has yielded two interesting mutants, Sleepy, which sleeps excessively, and Dreamless, which lacks rapid eye movement (REM) sleep. The...

NEWS Jun 22 2015

Studies Find Early European Had Recent Neanderthal Ancestor

In 2002, archaeologists discovered the jawbone of a human who lived in Europe about 40,000 years ago. Geneticists have now analyzed ancient DNA from that jawbone and learned that it belonged to a...

NEWS Jun 14 1996

Genetic Cause of Most Common Cancer Found

Institute researchers have learned that basal cell carcinoma, the most common human cancer, is caused by a defect in a gene that restrains cell growth. The finding could lead to new drugs--perhaps...

NEWS May 2 2016

The Genetic History of Ice Age Europe

Analyses of ancient DNA from prehistoric humans paint a picture of dramatic population change in Europe from 45,000 to 7,000 years ago, according to a new study led by Howard Hughes Medical...

NEWS Aug 10 2017

Genetically Engineered Ants Showcase Smell’s Role in Social Behavior

Without a sense of smell, female ants wander off on their own, mooch crickets caught by others, and refuse to mate. These mutant insects are adrift in society, living lives seemingly separate from...

NEWS May 1 1997

Prenatal Genetic Test Analyzes DNA from Fetal Cells

Hughes researchers have designed a prenatal blood test to diagnose a fetus at risk for developing sickle cell anemia or β-thalassemia.To test a fetus for a genetic disorder, doctors collect fetal...

NEWS Nov 25 1998

New Insight Into Genetic Cause of Infant Mortality

Four years ago, researchers identified a genetic mutation associated with spinal muscular atrophy (SMA), an inherited neuromuscular disease that is the most common genetic cause of infant mortality....

NEWS Apr 25 1996

Chernobyl's Grim Genetic Legacy

Sir Alec Jeffreys shared some bad news on the 10th anniversary of the worst nuclear power accident in history. The British geneticist and his Russian colleague, Yuri Dubrova, reported that mutation...

NEWS May 1 1998

Genetic Mutation Causes Heart Failure

HHMI researchers have discovered a genetic mutation that damages heart muscle so that it dilates to the point where the heart can no longer pump blood.The discovery may have immediate significance...

BULLETIN ARTICLE May 1 2015

Autism’s Genetic Roots

Autism is notorious for the broad range and variable intensity of symptoms that can impair a child’s behavior, communication, and social interactions. Scientists have long known that...

NEWS May 1 2011

Homing in on a Genetic Cause of Severe Glaucoma

More than half of the cases of blindness due to glaucoma are a result of angle-closure glaucoma (ACG), a less common but far more serious form of the disease. Until now, researchers have made little...

NEWS Feb 17 2008

New Genetic Syndrome Linked to Missing DNA

People who lack a certain large segment of DNA have a previously unrecognized syndrome characterized by mental retardation, seizures, and slight physical abnormalities, according to a genetic...

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The TALE of New Tools to Study Gene Regulation

Scientists Discover Gene Mutation Common in a Class of Ovarian Cancers

New Tools Will Drive Greater Understanding of Wheat Genes

Clock Gene May Connect Mood and Sleep

Left or Right? The Brain Knows Before You Move

How the African Striped Mouse Got Its Stripes

New Role for Fragile X Protein Could Offer Clues for Treatment

Locating a Genetic Glitch

Blazing a Genetic Trail

Genetic Tool Reaps Rich Harvest

Genetics of Head and Neck Cancers Discovered

Speedy Genetics Reveals Stem Cell Twists

Whole Genome Sequencing Identifies New Genetic Signature for Autism

Mouse Mutants May Shed Light on the Mysteries of Sleep

Studies Find Early European Had Recent Neanderthal Ancestor

Genetic Cause of Most Common Cancer Found

The Genetic History of Ice Age Europe

Genetically Engineered Ants Showcase Smell’s Role in Social Behavior

Prenatal Genetic Test Analyzes DNA from Fetal Cells

New Insight Into Genetic Cause of Infant Mortality

Chernobyl's Grim Genetic Legacy

Genetic Mutation Causes Heart Failure

Autism’s Genetic Roots

Homing in on a Genetic Cause of Severe Glaucoma

New Genetic Syndrome Linked to Missing DNA

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Type

The TALE of New Tools to Study Gene Regulation

Scientists Discover Gene Mutation Common in a Class of Ovarian Cancers

New Tools Will Drive Greater Understanding of Wheat Genes

Clock Gene May Connect Mood and Sleep

Left or Right? The Brain Knows Before You Move

How the African Striped Mouse Got Its Stripes

New Role for Fragile X Protein Could Offer Clues for Treatment

Locating a Genetic Glitch

Blazing a Genetic Trail

Genetic Tool Reaps Rich Harvest

Genetics of Head and Neck Cancers Discovered

Speedy Genetics Reveals Stem Cell Twists

Whole Genome Sequencing Identifies New Genetic Signature for Autism

Mouse Mutants May Shed Light on the Mysteries of Sleep

Studies Find Early European Had Recent Neanderthal Ancestor

Genetic Cause of Most Common Cancer Found

The Genetic History of Ice Age Europe

Genetically Engineered Ants Showcase Smell’s Role in Social Behavior

Prenatal Genetic Test Analyzes DNA from Fetal Cells

New Insight Into Genetic Cause of Infant Mortality

Chernobyl's Grim Genetic Legacy

Genetic Mutation Causes Heart Failure

Autism’s Genetic Roots

Homing in on a Genetic Cause of Severe Glaucoma

New Genetic Syndrome Linked to Missing DNA

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