Ferroptosis is a newly described iron-dependent form of cell death with far-reaching implications for both healthy physiology and disease. Whitney Henry investigates the fundamental biology of ferroptosis to understand when, where, and why it occurs. Her lab studies the factors that regulate a cell’s susceptibility to ferroptosis across diverse biological contexts, from therapy-resistant cancers and fatty liver disease to the menstrual cycle. By uncovering how ferroptosis may influence tissue function, immune responses, and regeneration, her research aims to advance our understanding of how metabolism, oxidative stress, and cell death converge to impact cell fate.