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Sean Morrison wants to understand the mechanisms that regulate stem cell self-renewal and how cancer cells hijack these mechanisms to enable tumor formation. To do this, Morrison and his team compare the processes by which stem cells and cancer cells replicate themselves. They are also studying the influence of aging on these processes. A more detailed understanding of these mechanisms has the potential to yield new therapies for regenerative medicine, by promoting stem cell self-renewal in the context of tissue injury, and in cancer, by inhibiting these mechanisms.