Current Research
Innate Immunity and Bacterial Pathogenesis

Russell Vance wants to understand how the innate immune system detects the presence of infectious microbes. Using a variety of experimental techniques, from structural biology to biochemistry to genetics to in vivo studies, Vance and his team dissect the fundamental mechanisms that provide host defense against bacterial infection. They are particularly interested in pathogen sensors situated in the cytosol of host cells. They are also interested in how the immune system detects pathogen-encoded activities.

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