Current Research
Mechanisms of mRNA Biogenesis, Function, and Degradation

Roy Parker wants to understand how cells regulate the biogenesis, function, and degradation of both messenger RNAs, or mRNAs, and non-coding RNAs. One major project for Parker and his team is to understand the structure, composition, dynamics, and biological functions of ribonucleoprotein (RNP) granules – membraneless compartments that play roles in RNA localization, RNP biogenesis, and memory formation.  RNP granules, when aberrant, contribute to neurodegenerative diseases. The team is also focused on a project examining the mechanisms controlling the stability of non-coding RNAs and their impact on human disease. 

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