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Rachel Wilson wants to understand how neural computations are implemented at the level of network connectivity patterns, synapses, and ion channels. Wilson and her team are currently focusing on the neural computations involved in Drosophila navigation behavior. They use electrophysiology and optical physiology to monitor neural activity in behaving flies, as well as brain-wide connectomics analyses and computational modeling. Their goal is to develop an integrated mechanistic understanding of how navigation paths are guided by multimodal external sensory cues, internal drives, and remembered information.