Current Research
Adaptive and Innate Immune Responses in Humans

Michel Nussenzweig is interested in the molecular aspects of the immune system’s innate and adaptive responses. Using an approach combining biochemistry, molecular biology, and genetics, Nussenzweig and his team focus on B lymphocytes and antibodies to HIV-1 in their work on adaptive immunity, while their studies of innate immunity focus on dendritic cells. Through their work they aim to achieve a detailed understanding of the molecular basis of antibody production and the pathway of human dendritic cell development and differentiation. The team’s findings may help improve the effectiveness of vaccines for pathogens and therapies to prevent or control auto-immunity.

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