Skip to main content

Meng Wang wants to reveal the fundamental mechanisms of organism aging, lipid metabolism, and reproductive senescence. These intertwined biological processes exert profound influence on human health and factor into various chronic and degenerative diseases. Wang’s team investigates the molecular mechanisms governing these key biological processes and their complex interrelationship, by combining the power of functional genomics in the worm C. elegans with metabolomics, chemical engineering, and optical biophysics. Through their work, the team is: advancing understanding of metabolite signaling in organelles, microbiome-host interaction, and olfactory regulation; developing innovative imaging platforms for in vivo metabolite fingerprinting; and seeking to identify effective metabolites for improving an organism’s health span.