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Loren Looger uses protein engineering to create tools for studying and manipulating the brain and other biological samples. Looger’s team combines computational and evolutionary methods to create new reagents for use in characterizing and manipulating the assembly and function of neural circuits. The team designs and tests these reagents – and other tools – in collaboration with other scientists. Their projects include creating sensors for calcium, neurotransmitters, and neuromodulators; optogenetic effectors; engineered viral capsids; probes for EM and immunolabeling; and recently, designed proteins and pathways for carbon capture and other environmental remediation. Ultimately, the team’s goal is to enable better science in diverse fields and across the globe through collaboration and innovation.