Current Research
Mentor: Jacob Scott, MD, DPhil
So long as humans use antibiotics to fight bacteria, antibiotic resistance will be with us. Kyle Card is using bacteria from various stages of the seminal E. coli long-term evolution experiment (LTEE) – which has tracked bacterial evolution over more than 70,000 generations – to examine how bacteria’s evolutionary history, together with population size and mutation rates, contribute to the evolution of antibiotic resistance and associated fitness costs.