Krishna Shenoy wants to better understand how the brain controls movement. Shenoy and his team also want to design medical systems – termed brain-machine interfaces or brain-computer interfaces (BCIs) – to assist people with paralysis. The team investigates the neural basis of movement preparation and generation using a combination of electrophysiological, behavioral, computational, and theoretical techniques. Their neuroengineering research focuses on the design of cortical implants that translate neural activity into control signals for prosthetics that aim to restore individuals’ lost motor function due to paralysis. They also use clinical trials to discover human-only neural encoding strategies and test how their BCI designs work in real-world settings.