Jorge Dubcovsky investigates the developmental processes and disease-resistance gene networks that affect wheat growth and productivity. Using genomic tools, Dubcovsky’s team has mapped, isolated, and cloned developmental genes involved in flowering initiation, spike development, and senescence. By dissecting wheat gene networks and creating a public mutation database, his work is helping breed varieties of wheat that are more nutritious, resistant to pathogens, and better able to adapt to our changing climate.
Researchers know how to make precise genetic changes within the genomes of crops, but the transformed cells often refuse to grow into plants. One team has devised a new solution. HHMI scientists develop a much-needed genetic resource that is aiding development of wheat plants with improved traits. Scientists have identified a gene that enables wheat crops to fight off stem rust, a dreaded fungus that blights wheat fields with rusty brown lesions and reduces yields. Fifteen scientists working in the plant sciences gain flexible support from HHMI and the Gordon and Betty Moore Foundation to move their research in creative new directions.