Current Research
A mechanistic understanding of a behaviorally relevant brain function

Jeffrey Magee is attempting to produce biophysically-based explanations to elucidate many of the ways in which the physical properties of single and small networks of nerve cells enable them to process and store information. Magee and his team use a variety of optical approaches (two-photon transmitter uncaging, single and two-photon channel rhodopsin-2 (ChR2) and halorhodopsin (NpHR) pump activation, and two-photon Ca2+ imaging) and electrical techniques (dual whole-cell recordings, cell-attached, and outside-out patches) in their work.

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