Current Research
Understanding Cellular Metabolic Control
Jared Rutter wants to define the molecules and their interactions that enable cellular metabolic control. Rutter and his team are currently exploring two central aspects of this research: deciphering how metabolic control is enacted at the level of mitochondria and leveraging this knowledge to explore the connection between metabolism and cellular behaviors. Specifically, the team seeks to determine how alterations in distinct metabolic pathways can impact cell fate and behavior decisions, with implications for human diseases such as cancer and heart failure. To do this, they are developing experimental and computational platforms to identify and characterize novel features and effects of metabolism.