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Jan Funke develops methods and tools to analyze vast microscopy image data sets. Specifically, Funke and his team automatize computer-vision and machine-learning techniques that are designed to work hand in hand with human annotators. Their aim is to prioritize accuracy, speed, and scalability, while overcoming challenges such as poor resolution and other ambiguities. In addition, the team wants to use statistics extracted from automatic reconstructions of biological structures to test hypotheses of accuracy and improve human proofreading.