Mentor: David Langenau, PhD
James Allen is working to understand how pediatric cancers, such as T-cell acute lymphoblastic leukemia, or T-ALL, co-opt our body’s mechanisms for their own ends. A major hurdle to developing a more effective treatment for T-ALL is a limited understanding of the genes and pathways that drive the cancer’s spread and are required for tumor growth. Allen plans to uncover novel drivers of the disease and identify pathways that can be targeted by therapeutics.