Current Research
Mechanisms of Neuronal Membrane Trafficking and Synaptic Function
Edwin Chapman is interested in the molecular mechanisms underlying neuronal membrane fusion, synaptic transmission, and synaptic plasticity. Chapman and his team are focused on elucidating the mechanisms that mediate calcium-triggered exocytosis in neurons and neuroendocrine cells, as well as a number of related membrane trafficking and synaptic function questions. They use a range of techniques in their work, including multiple single-molecule approaches, steady-state and time-resolved fluorescence spectroscopy, and live-cell imaging and electrophysiology.