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Dyche Mullins is interested in the assembly and regulation of cytoskeletal networks and the roles they play in living cells. Mullins and his team seek to understand how collections of macromolecules work together to establish long-range order in cells, through dynamic self-assembly into much larger structures such as membranes and cell walls. Using advanced imaging techniques and mechano-biochemistry approaches, the team investigates amoeboid cell migration, assembly and disassembly of dendritic actin networks, and movement of intracellular cargo in bacteria, among other projects.