Skip to main content

David Liu integrates chemistry and evolution to advance our understanding of biology and to enable new therapeutics. His research team’s work includes: the engineering and delivery of genome editing proteins, such as base editors, to study and treat genetic diseases; the use of phage-assisted continuous evolution (PACE) for proteins with novel therapeutic potential; and the use of DNA-templated organic synthesis to discover bioactive synthetic small molecules and synthetic polymers. These technologies – base editing, PACE, and DNA-templated synthesis – were pioneered in Liu’s laboratory.