Cagla Eroglu is seeking to elucidate new principles of brain development based on how cells called astrocytes guide the assembly and function of synaptic circuits underlying cognition. Eroglu’s team is developing new techniques to visualize astrocytes and study astrocyte-neuron interactions. Currently, they are working to identify novel molecular mechanisms by which astrocyte morphogenesis and maturation are coupled to synapse development and function. The team has revealed that a combined astrocyte-neuron chemo-affinity code regulates synaptic wiring. Eroglu’s work has implications for understanding autism and other disorders rooted in brain connectivity.