Current Research
Mechanisms of Immune Control in HIV Infection

Bruce Walker’s research is focused on learning from patients to define mechanisms of immune system control of chronic viral infections, with an emphasis on those who control HIV infection in the absence of antiviral therapy. Through an international collaboration, Walker and his team are investigating the immunologic, virologic, and host genetic mechanisms that account for this phenotype. They are applying their discoveries to prophylactic and therapeutic vaccine development, and to define specific antiviral responses of various subsets of immune cells. Walker also directs population-based research studies on HIV infection at South Africa’s Nelson Mandela School of Medicine.

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