Current Research
The Regulation and Role of Autophagy in Disease

Beth Levine seeks to understand the regulation and functions of autophagy, the body’s process of degrading and recycling damaged cellular components. Levine and her team use approaches from biochemistry, cell biology, physiology, and genetics to study the essential autophagy protein Beclin 1, as well as mediators of selective forms of autophagy. The team studies the regulation of these proteins, as well as the molecular mechanisms by which the proteins protect against cancer, infectious diseases, aging, metabolic disorders, and neurodegenerative diseases. In addition, they are developing strategies to increase autophagy to improve human health.

Find a Scientist