Alison Tebo is interested in using protein engineering to develop chemical biology tools that can sense and manipulate biological processes. In particular, Tebo and her team focus on tools that can be used to decipher the interactions of different types of cells – their signaling and metabolite exchange processes, migration patterns, and interplay with other cell types, intruders, and their environment. To that end, they are currently exploring projects related to affinity reagents, manipulation of enzyme activity, and manipulation and detection of cell-cell and cell-matrix interactions.
HHMI Janelia Research Campus Group Leaders Alison Tebo and Srinivas Turaga are creating new AI models to optimize the development of sensors used to track biological processes happening inside cells in real time – key tools used to understand how the body and brain work.