Current Research
The Molecular Basis of Regeneration

Alejandro Sánchez Alvarado is interested in the molecular and cellular mechanisms underpinning animal regeneration. To address this long-standing problem of biology, Sánchez Alvarado and his team use the planarian Schmidtea mediterraea as a model system. The team has developed a range of molecular tools to study this animal’s regenerative capacity, which is driven by a population of collectively totipotent stem cells. Through their systematic cellular and molecular genetic studies, the team is gaining insights into biological properties crucial not only to regeneration, but also to the normal development of higher organisms, including humans.

Find a Scientist