Harald Hess is interested in developing high-throughput 3D electron microscopy and super-resolution 3D optical microscopy for use in brain connectomics and cell biology. Hess and his team work closely with researchers at Janelia and elsewhere to devise systems that transcend the challenges associated with imaging living biological systems. By taking a coherent systems approach to such challenges, the team aims to bridge diverse fields, nucleate and drive collaborations, and be driven by new research opportunities identified by scientists worldwide.
Janelia’s COSEM Project Team has created a set of tools to make annotated 3D images of cells, showing the relationships between different organelles. The method melds the best of super-resolution fluorescence and electron microscopy to show how proteins relate to cells’ fine structure. Janelia group leader Eric Betzig wins Nobel Prize for the development of super-resolved fluorescence microscopy. Over the past year, two scientists who have been at Janelia since its opening took on new roles as group leaders, and six new fellows were recruited to head their own research groups.