Computers can predict the detailed structure of small proteins nearly as well as experimental methods, at least some of the time, according to new studies by HHMI researchers. The findings provide a glimmer of hope that scientists eventually may be able to determine the structure of proteins from their genomic sequences, a problem that has seemed insurmountable.
HHMI researchers have discovered a new culprit that can induce instability in the genome and thereby set the stage for cancer to develop.
Using lasers, tiny beads and a Lego set, HHMI researchers have made the first measurement of the torsional, or twisting, elasticity of a single molecule of DNA.
HHMI researchers discover new details about how the immune system generates antibodies.
Releasing the "brakes" on cells of the immune system can boost the ability of cancer vaccines to target tumors.
HHMI researchers and their colleagues identify a new culprit in long QT syndrome, which can cause fatal heart arrhythmia.
Gene mutation that produces a black coat color in mice also causes degeneration of neurons similar to that observed in Creutzfeldt-Jakob and mad cow disease.