Malaria parasites infecting human red blood cells send packets of information between cells to coordinate group activity. When the parasites are under stress, the communication increases their ability to develop into a new stage of the life cycle.
HHMI selects 13 of the world’s leading basic science researchers to receive Senior International Research Scholar (SIRS) awards. The awards support outstanding biomedical scientists working outside the United States who have made significant contributions to fundamental research in the biological sciences.
Two groups of HHMI scientists working independently have identified a critical enzyme that allows a malaria-causing parasite to take over and thrive in human red blood cells.
Dos grupos de científicos del HHMI que trabajaban de forma independiente han identificado una enzima crítica que permite que el parásito que causa la malaria controle los glóbulos rojos sanguíneos humanos y prospere en el interior de los mismos.
HHMI international scholar Alan Cowman has set out to understand the proteins that oversee malaria's destruction and rebuilding of red blood cells.
A molecule that constantly reinvents itself is one of the many ingenious mechanisms that the malaria parasite has evolved to protect itself against the human immune system.
HHMI international research scholars have determined how the malaria parasite can turn on one cloaking gene and silence dozens of others until they are needed.
Becarios internacionales de investigación del HHMI determinan la forma en la que el parásito de la malaria puede activar un gen de encubrimiento y mantener a docenas de genes en silencio hasta que sean necesitados.
Researchers identify a gene that the malaria parasite uses to switch back and forth between invasion pathways.
Scientists are learning how the malaria parasite Plasmodium falciparum disguises itself to avoid detection by the immune system.
The malaria parasite survives in its host by remodeling the red blood cells in which it dwells. The mechanism that enables it to do that may provide a novel target for anti-malaria therapy.