HHMI selects 13 of the world’s leading basic science researchers to receive Senior International Research Scholar (SIRS) awards. The awards support outstanding biomedical scientists working outside the United States who have made significant contributions to fundamental research in the biological sciences.
Some bacteria take over cells by interfering with an important process called SUMOylation, which helps cells respond to stress.
HHMI scientists have taken a major step towards understanding the molecular mechanisms that transform Listeria monocytogenes from a harmless soil-dweller to a dangerous human pathogen by mapping the genes that Listeria expresses under different environmental conditions.
Researchers have learned how Listeria crosses the placenta from mother to baby.
New research by a team of French and U.S. scientists has identified both the bacterial and host receptor proteins that enable Rickettsia conorii, which causes Mediterranean spotted fever, to enter cells.
Nueva investigación de un equipo de científicos franceses y estadounidenses identifica la proteína bacteriana y el receptor del huésped que permiten que la Rickettsia conorii, que causa la fiebre botonosa mediterránea, entre a las células.
Scientists taking a close look at how a dangerous food-borne bacterium invades the gut have identified a new culprit, a molecule that normally helps hold the intestinal lining and other sheets of epithelial cells together.
El microbio infeccioso Listeria monocitogenes se adueña de la maquinaria de transporte celular para invadir las células y esconderse del sistema inmune.
The infectious microbe Listeria monocytogenes commandeers cellular transport machinery to invade cells and hide out from the immune system.