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Loren Frank’s HHMI lab at UCSF has pioneered an ambitious framework for sharing vast neuroscience datasets and complicated analysis methods, a step towards tipping the culture of science towards more effective and fruitful collaboration. Precision genome editing tools – including prime editing – enable scientists to model genetic variants in their native environment. Now, researchers have developed a framework for engineering and measuring the effects of thousands of genetic mutations simultaneously while accurately quantifying the efficiency of prime editing. They’ve even found that some mutations once considered to be inconsequential or nonpathogenic may contribute to cancers. HHMI Professor Marla Geha launched a first-of-its-kind program at Yale that provides military veterans hands-on research experience in their undergraduate years. The program will welcome a new cohort this summer.The program recognizes early career faculty who are committed to advancing inclusivity in science. Each Scholar is appointed for up to two five-year terms, receiving up to $8.6 million in total support over 10 years.HHMI Investigator Sangeeta Bhatia’s lab developed a low-cost, point-of-care platform to detect lung cancer via a simple urine test. Penniman brings more than 25 years of leadership in nonprofit and human health communications.The program provides up to $1.5 million in support for early career scientists who have the potential to become inclusive leaders in academic research.More than 50 colleges and universities embarked on a five-year journey, each funded by $1 million grants from HHMI, to build strong support systems for encouraging student participation in science. Read the Inclusive Excellence 1 & 2 capstone report, which highlights what the schools have learned and accomplished, and what challenges remain.Humans and many other organisms depend on molecular systems that cut and reconnect their genetic material. A new study explores the workings of an ancient splicing mechanism still present in bacterial cells. The second round of $2.5 million grants were awarded to research universities working to build inclusive learning environments for students in science, technology, engineering, and mathematics (STEM).
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