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[ Vol. 26 No. 1 ]
FEATURED
One Foot in Front of the Other

Inside cells, specialized proteins march down a network of highways carrying machinery and messages. Researchers are learning how they manage it.

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In This Issue

Rational Exuberance
 
with video
A Structural Revolution
 
with slideshow
A Happy Oasis
 
with video
Rickety for a Reason
 
with sidebar
Sister Act
 
Cellular Search Engine
 
with Sidebar
Contributors
Trash Is Treasure

Landfill-bound materials take a detour to enliven classroom learning. 

The Past, Present, and Future Earth

The 2012 Holiday Lectures on Science explores our changing planet.

A Trick of Light
miniSOG, a protein label used in microscopy, can also trigger cell death on demand. 

Articles

Tunneling Out

Bulky RNA–protein particles take a surprising route through the nuclear membrane.

Melody-Modifying Mice

An unexpected brain connection reveals that mice can learn new features of their songs.

A Time to Transcribe

In the mouse liver, almost all DNA transcription occurs at the same time every day.

Briefs

An Immunological Arms Race
The Origins of Doubt
Sick Snake Science
Getting to the Root of Things
Kinetochore Structure: A Sizable Problem
A Toxic Environment for Kidneys
A Fruit Ripening Mystery

Perspectives & Opinions

How do you encourage innovation in your lab?

Great scientists are also great innovators. New ideas, techniques, and devices form the bedrock of scientific discovery. Here, four researchers share how they inspire innovation in the lab.

Model of Success

Taking inspiration from the best.

President's Message

Taking the Long View
by Robert Tjian, PhD