New: The student document is a fillable PDF form. Students can type their answers in the document and upload images saved as PDFs. (Note: If you print the document it will look just like a regular document.)
This activity is part of a series of activities and demonstrations focusing on various aspects of the human immunodeficiency virus (HIV) life cycle.
HIV is a retrovirus. Retroviruses are distinguished from other types of viruses by two key steps in the replication cycle: reverse transcription and integration. After HIV infects a host cell, reverse transcription results in the production of a double-stranded DNA copy of the single-stranded HIV RNA genome. Integration results in the insertion of the HIV DNA into a region of the host genome.
In this activity, students model the integration step.
This activity requires pop beads or pipe cleaners. It was designed to be completed in a 50-minute class period and is appropriate for all levels of high school biology.