- NGSS (2013) LS
- MS-LS1-5, MS-LS4-4, MS-LS1.A, MS- LS2.A, MS-LS3.B, MS-LS4.B, MS- LS4.C, HS-LS4-2, HS-LS4-4, HS-LS1.A, HS-LS3.B, HS-LS4.B, HS-LS4.C
- Common Core (2010)
- CCSS.ELA-Literacy.RH.9-10.3, CCSS.ELA-Literacy.RH.9-10.4, CCSS.ELA-Literacy.RH.11-12.2, CCSS.ELA-Literacy.RST.11-12.4, CCSS.ELA-Literacy.WHST.9-12.2, CCSS.ELA-Literacy.W.9-10.2
- AP Biology (2012-2013)
- 1.A.1, 1.A.2, 1.A.4, 1.C.3, 3.A.3, 3.C.1, 3.C.2, 4.C.1
- IB Biology (2009)
- 4.1, 4.3, 5.4, D.2
201Film GuideFilm Guides: Natural Selection in HumansThe following classroom-ready resources complement The Making of the Fittest: Natural Selection in Humans, which describes the connection between malaria and sickle cell anemia—one of the best-understood examples of natural selection in humans. Also available in Spanish.
698ActivityMendelian Genetics, Probability, Pedigree, and Chi-Square StatisticsA lesson that requires students to work through a series of questions pertaining to the genetics of sickle cell disease and its relationship to malaria. These questions will probe students' understanding of Mendelian genetics, probability, pedigree analysis, and chi-square statistics. Also available in Spanish.
23ActivityHow Do Fibers Form?A hands-on activity in which students construct models of sickle-cell hemoglobin fibers inside red blood cells to illustrate how changes in the structure of a protein can affect cell shape. Students are then asked to relate these changes to disease symptoms. Also available in Spanish.