The different rates at which β-amyloid (Aβ) was cleared from the brains of mice that were awake, sleeping, or in an induced sleep state using the anesthetic ketamine/xylazine (KX). The * indicates a P value < 0.05, meaning that the differences in clearance rates are statistically significant in this study. The error bars represent standard error of the mean.
The accompanying downloadable Educator Materials PDF, which includes background information, graph interpretation and discussion questions, and the Student Handout, which includes the image and background information, have been remediated to comply with Section 508 of the National Rehabilitation Act for accessibility and can be used with screen readers.Figure 3B from:
Xie et al. Sleep drives metabolite clearance from the adult brain. Science 342 (6156), 373-377.