The different rates at which β-amyloid (Aβ) was cleared from the brains of mice that were awake, sleeping, or in an induced sleep state using the anesthetic ketamine/xylazine (KX). The * indicates a P value < 0.05, meaning that the differences in clearance rates are statistically significant in this study. The error bars represent standard error of the mean.
The accompanying downloadable Educator Materials PDF includes background information, graph interpretation and discussion questions. The Student Handout includes the image and background information. Figure 3B from:
Xie et al. Sleep drives metabolite clearance from the adult brain. Science 342 (6156), 373-377.