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Sickle Cell Anemia

Sickle cell anemia is a genetic disease that affects hemoglobin. A single nucleotide change in the hemoglobin gene causes an amino acid substitution in the hemoglobin protein from glutamic acid to valine. The resulting proteins stick together to form long fibers and distort the shape of the red blood cells.

Curriculum Connections:

AP Biology (2015)
1.B.1.a; 3.A.1.a,b; 3.C.1.a,b; 3.C.2.a; 4.A.1.a,b; 4.B.1.a

IB Biology (2016)
1.1, 2.3, 2.4, 2.6, 2.7, 3.2, 7.1, 7.2, 7.3, 10.1

NGSS (April 2013)
HS-LS1-1 (LS1.A), HS-LS1-4 (LS1.B), HS-LS3-2 (LS3.B), HS-LS4-1 (LS4.A)

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Additional Materials

Bulletin Article
Bulletin Article