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  • Cancer and Cell Fate in the Intestinal Epithelium

    Cancer and Cell Fate in the Intestinal Epithelium

    Animation

    (2 min 17 sec) Disrupting the normal processes of differentiation and maturation of the intestinal epithelial cells can lead to cancer. Also available in Spanish.

  • The p53 Gene and Cancer

    The p53 Gene and Cancer

    Click & Learn

    This Click and Learn explains the structure and function of the p53 protein as well as how the protein’s activity is regulated.

  • The Eukaryotic Cell Cycle and Cancer

    The Eukaryotic Cell Cycle and Cancer

    Click & Learn

    Explore the phases, checkpoints, and protein regulators of the cell cycle in this highly interactive Click and Learn and find out how mutated versions of these proteins can lead to the development of cancer. Also available in Spanish.

  • BCR-ABL: Cancer Protein Structure and Function

    BCR-ABL: Cancer Protein Structure and Function

    Click & Learn

    This Click and Learn describes how understanding the structure of the BCR-ABL kinase led to the development of an effective treatment for chronic myeloid leukemia.

  • Cell Division and Cancer Risk

    Cell Division and Cancer Risk

    Data Point

    Cancer is typically attributed to hereditary and environmental factors, but these only explain a fraction of overall cancer risk. In this study, researchers investigated how a third factor—chance genetic mutations that occur during stem cell division—may contribute to the overall rate of cancer incidence in different body tissues.

  • Cancer Discovery Activities

    Cancer Discovery Activities

    Activity

    These two hands-on activities are based on a Howard Hughes Medical Institute 2013 Holiday Lectures on Science video featuring researcher Dr. Charles L. Sawyers. Also available in Spanish.

  • How We Get Our Skin Color Interactive

    How We Get Our Skin Color Interactive

    Interactive Video

    (3 min 32 sec) This interactive animation about the biology of skin color provides stop points at which students can further explore the material through additional text and illustrations, videos, questions, and simple interactive widgets.

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