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  • White-Nose Syndrome

    White-Nose Syndrome

    Phenomenal Images

    Students explore images of bats with an infectious fungal disease as phenomena to learn about population dynamics and disease impacts.

  • White-Nose Syndrome in Bat Populations

    White-Nose Syndrome in Bat Populations

    Data Points

    Scientists modeled the impact of an infectious fungal disease on a bat population.

  • Age Structure of Ebola Outbreaks

    Age Structure of Ebola Outbreaks

    Data Points

    Scientists analyzed demographics, including sex and age, of the spread of the Ebola Virus Disease during seven outbreaks in the Democratic Republic of Congo.

  • A Wasp Mom’s Gift: Blankets of Bacteria

    A Wasp Mom’s Gift: Blankets of Bacteria

    Animated Shorts

    (9 min 10 sec) You don’t want to be a honeybee when the beewolf is on the prowl.

  • Mosquitoes Might SAVE Lives, Thanks To Bacteria

    Mosquitoes Might SAVE Lives, Thanks To Bacteria

    Animated Shorts

    (9 min 4 sec) Dengue fever is a deadly mosquito-borne virus that plagues the earth, but science is inching closer to an unlikely solution: bacteria.

  • Superbugs That Resist Antibiotics Can Evolve in 11 Days

    Superbugs That Resist Antibiotics Can Evolve in 11 Days

    Animated Shorts

    (8 min 50 sec) Antibiotics like penicillin have a critical role in medicine, but using them is not a decision to be taken lightly.

  • Virus Hunters: Epidemiology of Nipah Virus

    Virus Hunters: Epidemiology of Nipah Virus

    Case Studies

    In this activity, students will be exploring cases of Nipah virus (NiV) infection as an epidemiologist would, by collecting evidence and making calculations and predictions, based on scientific data.

  • Viral Lysis and Budding

    Viral Lysis and Budding

    Labs & Demos

    This activity outlines two demonstrations that model how enveloped and nonenveloped viruses are released from infected cells.

  • HIV Protease Inhibitors

    HIV Protease Inhibitors

    Labs & Demos

    This demonstration models how the HIV protease enzyme functions and how its activity is blocked by a class of anti-HIV drugs.

  • HIV Life Cycle Activities

    HIV Life Cycle Activities

    Collection

    A collection of activities and demonstrations focusing on various aspects of the human immunodeficiency virus (HIV) life cycle. They are designed to be completed individually or as part of the series...

  • Viral DNA Integration

    Viral DNA Integration

    Labs & Demos

    In this hands-on activity, students model how a double-stranded DNA copy of the HIV genome is integrated into the host cell DNA.

  • HIV Reverse Transcription and AZT

    HIV Reverse Transcription and AZT

    Card Activities

    Students model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

  • HIV Receptors and Co-receptors

    HIV Receptors and Co-receptors

    Labs & Demos

    This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

  • Think Like a Scientist: Natural Selection in an Outbreak

    Think Like a Scientist: Natural Selection in an Outbreak

    Scientists at Work

    (7 min 29 sec) This video focuses on the front lines of the 2013–2016 Ebola outbreak in West Africa and explains how scientists monitored the evolution of the virus by analyzing its genome.

  • Patterns of Zoonotic Disease

    Patterns of Zoonotic Disease

    Data Points

    In this study, scientists analyzed previously published data on terrestrial mammal zoonotic host species and the pathogens they carry to search for global patterns of zoonotic disease distribution.

  • Virus Explorer

    Virus Explorer

    Click & Learn

    Explore the similarities and differences of a variety of viruses by sorting them based on structure, genomic make-up, host range, transmission mechanism, and vaccine availability.

  • Virus Hunter: Monitoring Nipah Virus in Bat Populations

    Virus Hunter: Monitoring Nipah Virus in Bat Populations

    Scientists at Work

    (9 min 1 sec) In this video we follow scientists working in Bangladesh as they test fruit bat populations to determine whether they are infected with Nipah virus—a potentially deadly virus when passed on to humans.

  • Mosquito-Borne Viral Diseases

    Mosquito-Borne Viral Diseases

    Collection

    Most of the viral diseases transmitted by mosquitoes are caused by RNA viruses. One group of RNA viruses, the flavivirus, includes yellow fever, dengue, West Nile, Japanese encephalitis, St. Louis...

  • West Nile Virus: Vectors and Hosts Game

    West Nile Virus: Vectors and Hosts Game

    Card Activities

    This activity is a game that enacts the complexity of viral infections that involve different vectors and hosts.

  • Infectious Disease

    Infectious Disease

    Collection

    Engaging multimedia resources to teach about viruses, the immune systems, and infectious disease.

  • Rhinovirus

    Rhinovirus

    3D Models

    A 3D model of rhinovirus, an RNA genome virus that is the main cause of the common cold in humans.

  • Nodamura Virus

    Nodamura Virus

    3D Models

    A 3D model of nodamura virus.

  • Dengue Virus

    Dengue Virus

    3D Models

    A 3D model of dengue virus.

  • Teacher Guide: Immunology

    Teacher Guide: Immunology

    Resource Guides

    Topics include: Immunology, HIV immune response and drug development, ELISA, CCR5 co-receptor mutation, vaccine development, dengue fever, and immunological response

  • Malaria: Mosquito Host

    Malaria: Mosquito Host

    Animations

    (3 min 59 sec) A mosquito becomes infected with malaria when it sucks the blood from an infected human. Once inside the mosquito, the parasites reproduce in the gut and accumulate in the salivary glands, ready to infect another human host with the next bite.

  • Malaria: Human Host

    Malaria: Human Host

    Animations

    (4 min 18 sec) When a malaria-carrying mosquito bites a human host, the malaria parasite enters the bloodstream, multiplies in the liver cells, and is then released back into the bloodstream, where it infects and destroys red blood cells.

  • From Birds to People: The West Nile Virus Story

    From Birds to People: The West Nile Virus Story

    Click & Learn

    West Nile virus infects mosquitoes, birds, and people—with very different consequences.

  • The Making of the Fittest: Natural Selection in Humans

    The Making of the Fittest: Natural Selection in Humans

    Short Films

    (14 min 3 sec) This film explores the evolutionary connection between an infectious disease, malaria, and a genetic condition, sickle cell anemia.

  • Factors That Affect the Mosquito Life Cycle

    Factors That Affect the Mosquito Life Cycle

    Labs & Demos

    In this lab activity, students rear mosquitoes to test variables that might affect the mosquito life cycle.

  • The Mosquito Life Cycle Activity

    The Mosquito Life Cycle Activity

    Lessons

    In this activity, students study the mosquito life cycle by breeding and observing them and then demonstrate how these data could be used to inform public policy.

  • Stopping Mosquito-Borne Disease

    Stopping Mosquito-Borne Disease

    Click & Learn

    Learn about the nature of vector-borne diseases, and the life cycle of the dengue vector mosquito.

  • The Mosquito Life Cycle

    The Mosquito Life Cycle

    Clips

    (1 min 7 sec) To prevent mosquitoes from spreading diseases, it's essential to understand their life cycle.

  • Bee Colony Collapse Disorder

    Bee Colony Collapse Disorder

    Clips

    (7 min 46 sec) Charles Runckel, a graduate student in the DeRisi lab, uses the Virochip to examine the mystery of bee colony collapse disorder.

  • Structure of Dengue Virus

    Structure of Dengue Virus

    Animations

    (1 min 3 sec) The dengue virus's outer envelope proteins form symmetrical units and overlay the lipid envelope, capsid, and the RNA genome.

  • Dengue Virus Life Cycle

    Dengue Virus Life Cycle

    Animations

    (4 min 12 sec) Dengue virus has sophisticated mechanisms for entering a cell, for replicating its RNA genome, and for translating proteins.

  • Viral Geometry and Structural Diversity

    Viral Geometry and Structural Diversity

    Animations

    The geometric structures of viruses are beautiful and can be used, along with genomic information, to identify them.

  • HIV life cycle

    HIV life cycle

    Animations

    (4 min 52 sec) How HIV infects a cell and replicates itself using reverse transcriptase and the host's cellular machinery.

  • Antigen presentation and CTL

    Antigen presentation and CTL

    Animations

    (2 min 34 sec) How a cell infected by a virus signals cytotoxic T lymphocytes to kill the cell before the virus replicates and spreads.

  • Protease inhibitors

    Protease inhibitors

    Animations

    (1 min 6 sec) Protease inhibitors prevent maturation of viral proteins inside HIV particles.

  • AZT blocks reverse transcriptase

    AZT blocks reverse transcriptase

    Animations

    (1 min 46 sec) HIV's reverse transcriptase mistakes AZT for thymidine. Once incorporated, AZT stops reverse transcription.

  • Size Analogies of Bacteria and Viruses

    Size Analogies of Bacteria and Viruses

    Clips

    (1 min 44 sec) Dr. Finlay and Dr. Richard Ganem use physical analogies to compare the size of bacteria and viruses relative to a standard mammalian cell.

  • Penicillin acting on bacteria

    Penicillin acting on bacteria

    Clips

    (34 sec) Penicillin, as shown in this video, causes the cell walls of bacteria to rupture.

  • E. coli Infection Strategy

    E. coli Infection Strategy

    Animations

    (2 min 53 sec) Watch this animation to see the molecular tricks that an infectious strain of Escherichia coli uses to infect your gut.

  • Bacterial Conjugation

    Bacterial Conjugation

    Animations

    (23 sec) Bacteria can transfer genetic material, and thus drug resistance, to other bacteria via conjugation.

  • Recombination of Viral Genome

    Recombination of Viral Genome

    Animations

    (3 min 5 sec) When two different strains of influenza infect a single cell, their genetic material can mix freely, resulting in a new third strain of influenza.

  • Intracellular Infection by Salmonella

    Intracellular Infection by Salmonella

    Animations

    (1 min 19 sec) In this animation, you can see how one S. typhimurium invades an epithelial cell of the intestinal tract, survives the intracellular defense mechanisms of the host cell, and multiplies.

  • Viral Life Cycle

    Viral Life Cycle

    Animations

    (1 min 8 sec) This animation shows a single cycle of virus replication in a human cell.

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