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Showing 1-80 of 766 Resources
  • Understanding Science

    Understanding Science

    Click & Learn

    This interactive tool allows students and educators to document, annotate, and reflect upon their own and others' scientific research process.

  • Using the HHMI Mathematics and Statistics in Biology Guide in the Classroom

    Using statistics to analyze the data we generate from observations and experiments can be a daunting task for students — and for teachers. In my first eight years of teaching high school biology and...

  • Salt Stress Impacts Photosynthesis in Algae

    Salt Stress Impacts Photosynthesis in Algae

    Data Point

    Scientists investigated how salt affects the photosynthetic electron transport chain in freshwater green alga.

  • Winogradsky Column: Microbial Ecology in a Bottle

    Winogradsky Column: Microbial Ecology in a Bottle

    Click & Learn

    Explore this virtual Winogradsky column to learn about the diversity of microbes, microbial metabolic strategies, and geochemical gradients found in sediments.

  • Age Structure of Ebola Outbreaks

    Age Structure of Ebola Outbreaks

    Data Point

    Scientists analyzed demographics, including sex and age, of the spread of the Ebola Virus Disease during seven outbreaks in the Democratic Republic of Congo.

  • Using BioInteractive Resources Across A Semester Ecology Course

    One of my favorite aspects of HHMI BioInteractive resources is how they draw students into a story and engage them with real data and on-the-ground science. Within my ecology courses, I use numerous...

  • Mapping the Darién Gap

    Mapping the Darién Gap

    Scientists at Work

    (10 min 35 sec) Indigenous communities from the tropical rainforest of Darién, Panama use drones to map their land to protect it from outside threats and to make sustainable land use plans. Also available in Spanish.

  • Developing an Explanation for Mouse Fur Color

    Developing an Explanation for Mouse Fur Color

    Activity

    Students collect and analyze evidence for each of the major conditions for evolution by natural selection to develop an explanation for how populations change over time. 

  • Using BioInteractive to Generate Assessment Items

    What do I want my students to learn and how are they going to demonstrate what they’ve learned? Formative, summative, formal, informal — oh my! Prep time can be consumed with developing labs and...

  • Cystic Fibrosis Mechanism and Treatment

    Cystic Fibrosis Mechanism and Treatment

    Animation

    (2 min 31 sec) Mutations in the CFTR gene, which encodes a transmembrane ion channel, cause mucus buildup in the airways of patients with cystic fibrosis.

  • Film Guide for Nature’s Cutest Symbiosis: The Bobtail Squid

    Film Guide for Nature’s Cutest Symbiosis: The Bobtail Squid

    Film Guide

    The following classroom-ready resources complement the film Nature’s Cutest Symbiosis: The Bobtail Squid. It tells the story of the how the bobtail squid evolved to be able to avoid predators with the help of microbes.

  • Combining and Customizing BioInteractive Coral Bleaching Resources

    One of the goals of my introductory biology class is to introduce students to data skills alongside learning core concepts in ecology and evolution. I want my students to be able to summarize,...

  • CRISPR-Cas 9 Mechanism & Applications

    CRISPR-Cas 9 Mechanism & Applications

    Click & Learn

    Explore this dynamic interactive to learn the basic principles of how this revolutionary tool works and the many ways in which scientists are using it in their research.

  • Using Images as Phenomena

    Using Images as Phenomena

    Activity

    This hands-on activity engages students in asking questions about phenomena using images from the Image of the Week Collection.

  • Pelvic Evolution in Sticklebacks

    Pelvic Evolution in Sticklebacks

    Data Point

    Scientists used SNP genotyping in populations of freshwater stickleback fish to determine the genetic mutations responsible for the impaired development of pelvises and spines.

  • Scientific Inquiry and Data Analysis Using WildCam Gorongosa

    Scientific Inquiry and Data Analysis Using WildCam Gorongosa

    Activity

    In this activity, students will be guided through making observations from trail camera data in Gorongosa National Park, the development and investigation of a scientifically testable research question, and analysis of their results.

  • Biodiversity Studies in Gorongosa

    Biodiversity Studies in Gorongosa

    Activity

    In this activity, students will calculate species richness, evenness, and the Shannon diversity index for various habitat types using data from trail cameras in Gorongosa National Park, and then investigate the impact of human activity in these habitats.

  • Film Guide for Termites Digest Wood Thanks to Microbes

    Film Guide for Termites Digest Wood Thanks to Microbes

    Film Guide

    The following classroom-ready resources complement the film Termites Digest Wood Thanks To Microbes. It tells the story of the how termites evolved with the help of microbes passed down through a social behavior which enables them to digest wood.

  • A World Without Microbes: An Apocalyptic Thought Experiment

    A World Without Microbes: An Apocalyptic Thought Experiment

    Feature Film

    (7 min 1 sec) A world without microbes seems at first like a utopia without bacterial infections, mildew, or mold. But let’s take a deeper look.

  • Fecal Microbiota Transplants: The Ins and Outs of FMT

    Fecal Microbiota Transplants: The Ins and Outs of FMT

    Feature Film

    (7 min 21 sec) Poop. You flush it, and usually that’s the end of the story. But to scientists like Mark Smith, poop is more than just waste – it’s medicine.

  • Can a Fungus Save Plants from Global Warming?

    Can a Fungus Save Plants from Global Warming?

    Feature Film

    (8 min 2 sec) It’s about time we put plants into the spotlight and focus on one of their most critical microbial partners: Fungi.

  • Microbes from Mom — Vaginal Birth vs C-Section

    Microbes from Mom — Vaginal Birth vs C-Section

    Feature Film

    (9 min 13 sec) Do you remember your first birthday present? No? Good, because it’s gross.

  • Solving Crimes with the NECROBIOME

    Solving Crimes with the NECROBIOME

    Feature Film

    (7 min 10 sec) We can’t talk to the dead, but in their own way, the dead can speak to us.

  • Central Dogma Card Activity

    Central Dogma Card Activity

    Activity

    In this hands-on activity students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat genetic disease.

  • 3D Scan of Tiktaalik Fossil – Humerus

    3D Scan of Tiktaalik Fossil – Humerus

    3D Model

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil – Pelvis

    3D Scan of Tiktaalik Fossil – Pelvis

    3D Model

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil – Pectoral Fin

    3D Scan of Tiktaalik Fossil – Pectoral Fin

    3D Model

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil –  Body

    3D Scan of Tiktaalik Fossil – Body

    3D Model

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil –  Skull

    3D Scan of Tiktaalik Fossil – Skull

    3D Model

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • Monkey Social Status and Immune Response

    Monkey Social Status and Immune Response

    Data Point

    Scientists studied how the dominance ranking of female rhesus macaques living in social groups affected the expression of genes linked to immune response

  • Thank you for completing the NSTA 2018 Survey!

    Take a screenshot of this page and show it to someone at the BioInteractive booth (#323) to receive a stamp towards a free t-shirt.

  • Argumentation With Virus Explorer

    In 2000, scientists drilled a hole into the Siberian permafrost to collect soil samples estimated to be around 30,000 years old. Ten years later, the researchers added portions of these samples to...

  • Using the Identify and Interpret Strategy with Data Points

    I find that getting students excited about biology and engaging them in the practices of science can be challenging with certain topics. For example, with mitosis and the cell cycle, students...

  • Using BioInteractive Resources with English Learners

    Although I have no formal training as an English Learner teacher, I have, like many teachers in similar situations, taught dozens of EL students over the years. I have had plenty of formal training...

  • Data Points Guide

    Data Points Guide

    Teacher Guide

    A guide to BioInteractive’s Data Point resources aligned to relevant curriculum standards.

  • Scientists at Work Guide

    Scientists at Work Guide

    Teacher Guide

    A guide to BioInteractive’s Scientists at Work series of videos aligned to relevant curriculum standards.

  • New Laetoli Footprints and Hominin Body Size

    New Laetoli Footprints and Hominin Body Size

    Data Point

    Scientists were excavating a site in Laetoli, Tanzania when they uncovered two new sets of hominin tracks located about 150 meters south of the tracks found by Mary Leakey in the 1970’s. They estimated the heights of the two individuals using the size and shape of the footprints.

  • Film Guide for How Tube Worms Survive at Hydrothermal Vents

    Film Guide for How Tube Worms Survive at Hydrothermal Vents

    Film Guide

    The following classroom-ready resources complement the film How Tube Worms Survive in Hydrothermal Vents. It tells the story of the symbiotic relationship between the giant tube worm, Riftia pachyptila, and chemosynthetic bacteria.

  • Think Like a Scientist: Gorongosa

    Think Like a Scientist: Gorongosa

    Scientists at Work

    This short video tells the story of how a large-scale project to restore the wildlife of Gorongosa National Park began and describes the project’s approach of combining traditional conservation biology methods with solutions for addressing challenges in the community.

  • Nature’s Cutest Symbiosis: The Bobtail Squid

    Nature’s Cutest Symbiosis: The Bobtail Squid

    Feature Film

    (8 min 5 sec) The bobtail squid is an underwater delicacy for many predators, so the creature found a handy superpower to stay alive: Invisibility

  • Film Guide for Genes as Medicine

    Film Guide for Genes as Medicine

    Film Guide

    The following classroom-ready resources complement the film Genes as Medicine. It tells the story of the successes and challenges that led to the development of the first FDA-approved gene therapy for a genetic disease.

  • Niche Partitioning and DNA Metabarcoding

    Niche Partitioning and DNA Metabarcoding

    Click & Learn

    This interactive explores niche partitioning as a mechanism that enables similar species of animals to coexist.

  • Living Together

    Living Together

    Phenomenal Image

    Students explore photos of bobtail squid as an anchoring phenomenon to explore symbiosis and species interactions.

  • Maternal Microbiota Impacts Offspring Immune System

    Maternal Microbiota Impacts Offspring Immune System

    Data Point

    In this study, scientists compared two populations of pregnant mice, one which was kept germ-free throughout pregnancy and the other which was exposed during pregnancy to a strain of E. coli to determine whether the immune systems of offspring begin to develop in utero.

  • BioInteractive Online Professional Learning Course--Evolution

    BioInteractive Online Professional Learning Course--Evolution

    Online Professional Learning Course

    This asynchronous course is designed to help teachers deepen their content knowledge in evolution, and learn about exciting free classroom resources from BioInteractive.

  • Seed Dispersal in Tropical Forests

    Seed Dispersal in Tropical Forests

    Activity

    In this activity, students use data from published studies to understand patterns of seed dispersal and apply these ideas to the design of a conservation area.

  • Role of p53 in the Cell Cycle

    Role of p53 in the Cell Cycle

    Data Point

    Researchers investigated the role of p53 in cell cycle regulation by genetically engineering a cell line with deleted copies of the p53 gene. They exposed the cell lines to DNA-damaging radiation and observed how this exposure impacted mitosis.

  • The Search for a Mutated Gene

    The Search for a Mutated Gene

    Scientists at Work

    (8 min 54 sec) How do you identify the disease-causing mutation in a patient with an inherited disease? This video illustrates the steps involved—testing for genes that are the “usual suspects,” searching for mutations in novel genes, and assessing links between genotype and phenotype.

  • I Contain Multitudes: The Series

    I Contain Multitudes: The Series

    Collection

    I Contain Multitudes offers a new lens on life. With an eye on microbes—microscopic single-celled organisms—larger creatures such as ourselves suddenly look very different. Each of us is a more of a...

  • A Wasp Mom’s Gift: Blankets of Bacteria

    A Wasp Mom’s Gift: Blankets of Bacteria

    Feature Film

    (9 min 10 sec) You don’t want to be a honeybee when the beewolf is on the prowl.

  • Mosquitoes Might SAVE Lives, Thanks To Bacteria

    Mosquitoes Might SAVE Lives, Thanks To Bacteria

    Feature Film

    (9 min 4 sec) Dengue fever is a deadly mosquito-borne virus that plagues the earth, but science is inching closer to an unlikely solution: bacteria.

  • How Giant Tube Worms Survive at Hydrothermal Vents

    How Giant Tube Worms Survive at Hydrothermal Vents

    Feature Film

    (10 min 20 sec) Deep at the bottom of the Pacific Ocean, an amazing bacterial discovery reshaped our view of life on earth.

  • Superbugs That Resist Antibiotics Can Evolve in 11 Days

    Superbugs That Resist Antibiotics Can Evolve in 11 Days

    Feature Film

    (8 min 50 sec) Antibiotics like penicillin have a critical role in medicine, but using them is not a decision to be taken lightly.

  • Termites Digest Wood Thanks To Microbes

    Termites Digest Wood Thanks To Microbes

    Feature Film

    (7 min 11 sec) The next time you spot a termite chomping down on wood, know that they’re not dining alone.

  • Modeling Food Webs in Darién, Panama

    Modeling Food Webs in Darién, Panama

    Activity

    Students use cards to build model food webs and evaluate how ecological disturbances affect each trophic level. Also available in Spanish.

  • Genes as Medicine

    Genes as Medicine

    Short Film

    (17 min 16 sec) Watch the story of how gene therapy restored the sight of a nearly-blind young patient. Told from the perspective of two researchers who spent over 25 years working to develop this breakthrough technology, this short film chronicles their successes and challenges, and illustrates how the method works to treat inherited conditions.

  • Origins of Antibiotic Resistance

    Origins of Antibiotic Resistance

    Data Point

    Scientists collected bacteria from locations that had never been exposed to humans or modern antibiotics to determine if antibiotic resistance is newly evolved since the introduction of antibiotics or has evolved independently.

  • Identifying the Key Genes for Regeneration

    Identifying the Key Genes for Regeneration

    Scientists at Work

    (9 min 55 sec) Planarians have an amazing ability to regenerate lost tissues. In this video, scientists knock out two different genes in planaria to start to understand how the process works—and they generate animals with two heads and two tails!

  • Stalking the Genetic Basis of a Trait

    Stalking the Genetic Basis of a Trait

    Activity

    In this activity students analyze data on the expression of the tb1 gene and use it to formulate an explanation as to how a specific difference in the corn version of the gene explains the phenotype of less branching.

  • Vertebrate Declines and the Sixth Mass Extinction

    Vertebrate Declines and the Sixth Mass Extinction

    Data Point

    In this study, researchers measured species population declines on a global scale that may contribute to the sixth mass extinction.

  • BiomeViewer

    BiomeViewer

    Click & Learn

    An interactive to explore biomes, climate, biodiversity, and human impacts across the globe.

  • EarthViewer

    EarthViewer

    Click & Learn

    Download the accompanying student worksheet under "Downloads." What did Earth look like 250 million years ago? Or 1 billion years ago? Or 4.5 billion years ago? EarthViewer is an interactive tool that allows you to explore the science of Earth's deep history.

  • Virus Hunters: Epidemiology of Nipah Virus

    Virus Hunters: Epidemiology of Nipah Virus

    Activity

    In this activity, students will be exploring cases of Nipah virus (NiV) infection as an epidemiologist would, by collecting evidence and making calculations and predictions, based on scientific data.

  • Central Dogma and Genetic Medicine

    Central Dogma and Genetic Medicine

    Click & Learn

    This interactive uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat genetic diseases.

  • What van Leeuwenhoek Saw

    What van Leeuwenhoek Saw

    Activity

    This hands-on activity helps students understand concepts related to building scale models by using cards of microorganisms and cells that were first visualized by Antonie van Leeuwenhoek.

  • Predator-Prey Relationship Dynamics

    Predator-Prey Relationship Dynamics

    Data Point

    In a study in Greenland, scientists examined whether changes in population densities of Arctic fox are related to changes in population densities of its main prey, the lemming.

  • Tracking Genetically Modified Mosquitoes

    Tracking Genetically Modified Mosquitoes

    Activity

    Genetically modified mosquitoes have been used to reduce mosquito populations and the diseases they spread. But how can we tell if the method works? In this activity, students analyze data from a field experiment.

  • Microbial Community Response to an Oil Spill

    Microbial Community Response to an Oil Spill

    Data Point

    Researchers monitored the succession of the microbial community in the Gulf of Mexico using data from before, during, and after the Deepwater Horizon oil spill.

  • Population Dynamics

    Population Dynamics

    Click & Learn

    Explore the exponential and the logistic growth mathematical models that describe how population changes with time.

  • Benefits of Schools

    Benefits of Schools

    Phenomenal Image

    Students explore photos of animals in groups as anchoring phenomena to explore animal behavior concepts.

  • Using Wolbachia to Suppress Mosquito Fertility

    Using Wolbachia to Suppress Mosquito Fertility

    Data Point

    In this study, researchers tested whether releasing Wolbachia-infected male Aedes albopictus (Asian tiger mosquitoes) would suppress populations of this mosquito species in their study area.

  • How Lizards Find Their Way Home

    How Lizards Find Their Way Home

    Scientists at Work

    (8 min 33 sec) When Dr. Manuel Leal removed lizards from an area in the forest, he noticed an interesting phenomenon: all the lizards seemed to be back the next day. Watch as he sets up an experiment to study how these lizards navigate home. Also available in Spanish.

  • Seed Dispersal and Habitat Fragmentation

    Seed Dispersal and Habitat Fragmentation

    Scientists at Work

    (8 min 3 sec) Watch researchers follow brown spider monkeys in a tropical forest of Colombia to determine which plant seeds they are dispersing. Seed dispersers are critical to the forest’s ability to grow and regenerate. 

  • Root Movement

    Root Movement

    Phenomenal Image

    Students explore photos of plant cells as an anchoring phenomenon to explore the response of plant cells to stimuli.

  • WildCam Darién

    WildCam Darién

    Click & Learn

    Researchers in Darién and Soberanía National Parks use remote trail cameras to study jaguars and their prey. You can contribute to this important research through WildCam Darién, an online citizen science platform.

  • Sleep Clears β-amyloid from the Brain

    Sleep Clears β-amyloid from the Brain

    Data Point

    The researchers in this study tested whether the rate of Aβ removal is higher during sleep using mice as model organisms.

  • Modeling Trophic Cascades

    Modeling Trophic Cascades

    Activity

    Students use cards of animal and plant species to model trophic cascades. Species examples are drawn from seven different habitats to test student understanding.

  • Trophic Cascades in Salt Marsh Ecosystems

    Trophic Cascades in Salt Marsh Ecosystems

    Scientists at Work

    (10 min 1 sec) Ecologist Brian Silliman uses manipulative field experiments to reveal that salt marsh ecosystems are under top down control from consumers and predators.

  • Riverine Food Webs – How Flow Rates Affect Biomass

    Riverine Food Webs – How Flow Rates Affect Biomass

    Scientists at Work

    (9 min 15 sec) Ecologist Mary Power studies the Eel River in Northern California to figure out the connection between river flows and biodiversity.

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