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  • Role of p53 in the Cell Cycle

    Role of p53 in the Cell Cycle

    Data Points

    Researchers investigated the role of p53 in cell cycle regulation by genetically engineering cell lines with disrupted alleles of the p53 gene. They exposed the cell lines to DNA-damaging radiation and observed how this exposure impacted mitosis.

  • Cell Division and Cancer Risk

    Cell Division and Cancer Risk

    Data Points

    Cancer is typically attributed to hereditary and environmental factors, but these only explain a fraction of overall cancer risk. In this study, researchers investigated how a third factor—chance genetic mutations that occur during stem cell division—may contribute to the overall rate of cancer incidence in different body tissues.