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  • Role of p53 in the Cell Cycle

    Role of p53 in the Cell Cycle

    Data Points

    Researchers investigated the role of p53 in cell cycle regulation by genetically engineering a cell line with deleted copies of the p53 gene. They exposed the cell lines to DNA-damaging radiation and observed how this exposure impacted mitosis. Worksheets also available in Spanish.

  • Cell Division and Cancer Risk

    Cell Division and Cancer Risk

    Data Points

    Cancer is typically attributed to hereditary and environmental factors, but these only explain a fraction of overall cancer risk. In this study, researchers investigated how a third factor—chance genetic mutations that occur during stem cell division—may contribute to the overall rate of cancer incidence in different body tissues.