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  • Cystic Fibrosis Mechanism and Treatment

    Cystic Fibrosis Mechanism and Treatment

    Animations

    (2 min 31 sec) This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop treatments for the disease.

  • CRISPR-Cas 9 Mechanism & Applications

    CRISPR-Cas 9 Mechanism & Applications

    Click & Learn

    This interactive module explores how CRISPR-Cas9 technology works and the many ways in which scientists are using it in their research.

  • “Fixing” Gene Expression

    “Fixing” Gene Expression

    Card Activities

    In this hands-on activity, students review the steps of eukaryotic gene expression and learn how this knowledge can be used to treat different genetic conditions. The activity reinforces concepts covered in the Click & Learn “Central Dogma and Genetic Medicine.”

  • Activity for Genes as Medicine

    Activity for Genes as Medicine

    Film Activities

    This activity explores the content and research presented in the short film Genes as Medicine, which tells the story of how scientists succeeded in developing a gene therapy for a type of congenital blindness.

  • Niche Partitioning and DNA Metabarcoding

    Niche Partitioning and DNA Metabarcoding

    Click & Learn

    This interactive module explores niche partitioning, a mechanism that enables similar species of animals to coexist.

  • The Search for a Mutated Gene

    The Search for a Mutated Gene

    Scientists at Work

    (8 min 54 sec) This video describes the case of a patient with retinitis pigmentosa (RP), a progressive disease that leads to blindness, and how physician-scientist Dr. Ed Stone approached the search for the causal mutation.

  • Genes as Medicine

    Genes as Medicine

    Short Films

    (17 min 16 sec) This film describes the scientific principles and the research efforts involved in the development of a gene therapy for a congenital form of blindness, and how a young patient benefited from this medical breakthrough.

  • Identifying the Key Genes for Regeneration

    Identifying the Key Genes for Regeneration

    Scientists at Work

    (9 min 55 sec) This video describes how scientists silence different genes in regenerating planaria to study the process of regeneration at the molecular level.

  • Central Dogma and Genetic Medicine

    Central Dogma and Genetic Medicine

    Click & Learn

    This interactive module uses the central dogma as a model for exploring how modern molecular biology technologies can be used to treat different genetic conditions.

  • Tracking Genetically Modified Mosquitoes

    Tracking Genetically Modified Mosquitoes

    Lessons

    This activity challenges students to provide their questions and ideas for experiments they could conduct to investigate the impact of releasing genetically modified mosquitoes into the wild. It accompanies the video Genetically Modified Mosquitoes.

  • DNA Profiling Activity

    DNA Profiling Activity

    Case Studies

    This multipart activity is designed to give students a firm understanding of genetic profiling using short tandem repeats (STRs), which is a process used by forensics labs around the world.

  • Genetically Modified Mosquitoes

    Genetically Modified Mosquitoes

    Scientists at Work

    (8 min 35 sec) This video describes the process by which a line of genetically modified mosquitoes was engineered to reduce populations of wild mosquitoes.

  • Activity for The Double Helix

    Activity for The Double Helix

    Film Activities

    This activity explores the concepts and research presented in the short film The Double Helix, which tells the story of the discovery of the molecular structure of DNA.

  • Cone Snail Toxins and Paralysis

    Cone Snail Toxins and Paralysis

    Animations

    (3 min 28 sec) This animation shows how cone snail toxins cause paralysis by blocking signal transmission at the synapse between neuron and muscle.

  • Visualizing Gene-Expression Patterns

    Visualizing Gene-Expression Patterns

    Click & Learn

    This tutorial describes methods used to detect when and where genes are expressed in cells and tissues.

  • Immunology Virtual Lab

    Immunology Virtual Lab

    Virtual Labs

    This virtual lab teaches the procedures of performing an ELISA test to determine whether a particular antibody is present in a patient's blood sample.

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