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Showing 1-17 of 17 Resources
  • Cystic Fibrosis Mechanism and Treatment

    Cystic Fibrosis Mechanism and Treatment

    Animation

    (2 min 31 sec) Mutations in the CFTR gene, which encodes a transmembrane ion channel, cause mucus buildup in the airways of patients with cystic fibrosis.

  • Efficacy of a Treatment for Chronic Myeloid Leukemia

    Efficacy of a Treatment for Chronic Myeloid Leukemia

    Data Point

    Dr. Brian Druker and colleagues monitored white blood cell counts in six patients with chronic myeloid leukemia treated with the drug, STI571, which blocks the activity of the cancer-causing tyrosine kinase BCR-ABL.

  • Seeing Single Molecules Move

    Seeing Single Molecules Move

    Animation

    (1 min 40 sec) Single-molecule analysis using super-resolution microscopes reveals that transcription factors are not usually found bound to their binding sites on DNA.

  • Earth Systems Activity

    Earth Systems Activity

    Activity

    This activity guides students through building a conceptual model of how carbon dioxide affects Earth's climate

  • Film Guides: The Double Helix

    Film Guides: The Double Helix

    Film Guide

    The following classroom-ready resources complement The Double Helix. This short film describes the evidence that led James Watson and Francis Crick to the discovery of the double-helical structure of DNA and how the structure immediately revealed how genetic information is stored and inherited.

  • The Double Helix

    The Double Helix

    Short Film

    (16 min 53 sec) The Double Helix is the story of the scientists and evidence involved in one of the most important scientific quests of the 20th century: the discovery of the structure of DNA. Also available in Spanish.

  • Got Lactase? Blood Glucose Data Analysis

    Got Lactase? Blood Glucose Data Analysis

    Activity

    Students interpret the results of two different tests for lactase persistence.

  • The Day the Mesozoic Died

    The Day the Mesozoic Died

    Short Film

    (33 min 43 sec) The disappearance of the dinosaurs at the end of the Cretaceous period posed one of the greatest, long-standing scientific mysteries. This three-act film tells the story of the extraordinary detective work that solved it. Also available in Spanish.

  • Earth's Climate: Back to the Future

    Earth's Climate: Back to the Future

    Lecture

    (1 hr 27 min 59 sec) Earth has been both cooler and warmer in the past, but the change is usually gradual. The current rate of carbon dioxide increase is unprecedented in human history, and solutions to mitigate its effect on global warming are challenging to implement.

  • Calculating Iridium Fallout From an Asteroid Impact

    Calculating Iridium Fallout From an Asteroid Impact

    Activity

    A worksheet in which students calculate how much iridium was released, and eventually deposited all over the Earth, by the impact of the asteroid that caused the K-T extinction.

  • Polymerase chain reaction (PCR)

    Polymerase chain reaction (PCR)

    Animation

    (54 sec) PCR is a standard laboratory technique that allows amplification of specific segments of DNA based on complementarity.

  • Screening chemical libraries with robotics

    Screening chemical libraries with robotics

    Clip

    (1 min 24 sec) Robotic equipment makes it possible to screen massive chemical libraries in just a matter of days.

  • Visualizing Gene-Expression Patterns

    Visualizing Gene-Expression Patterns

    Click & Learn

    Learn about the different ways scientists are able to detect when genes are being expressed in various tissues.

  • Watson constructing base pair models

    Watson constructing base pair models

    Clip

    (1 min 42 sec) During the process of trying to elucidate the structure of DNA, Jim Watson made some cardboard models to try to understand how DNA nucleotides are paired. It helped him visualize how hydrogen atoms of paired nucleotides interact with each other to form a symmetrical structure that fits the double helix model.

  • Sanger method of DNA sequencing

    Sanger method of DNA sequencing

    Animation

    (52 sec) Fred Sanger developed the first technique for sequencing DNA. DNA is replicated in the presence of chemically altered versions of the A, C, G, and T bases. These bases stop the replication process when they are incorporated into the growing strand of DNA, resulting in varying lengths of short DNA. These short DNA strands are ordered by size, and by reading the end letters from the shortest to the longest piece, the whole sequence of the original DNA is revealed.

  • Polymerase chain reaction

    Polymerase chain reaction

    Animation

    (1 min 28 sec) Polymerase chain reaction, or PCR, is a technique for making many copies of a specific DNA sequence. DNA is repeatedly heated and cooled in the presence of primers that bracket the desired sequence and of the enzyme Tac polymerase. In as few as 30 cycles, a billion copies of the target sequence can be made.

  • Scanning Life's Matrix: Genes, Proteins, and Small Molecules

    Scanning Life's Matrix: Genes, Proteins, and Small Molecules

    Lecture

    In four presentations, Stuart L. Schreiber, PhD, and Eric S. Lander, PhD, open a window onto the fast-paced world of genomic science and chemical genetics.

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