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Showing 1-20 of 32 Resources
  • Living Together

    Living Together

    Phenomenal Images

    Students explore photos of bobtail squid as an anchoring phenomenon to explore symbiosis and species interactions.

  • The Eukaryotic Cell Cycle and Cancer

    The Eukaryotic Cell Cycle and Cancer

    Click & Learn

    Explore the phases, checkpoints, and protein regulators of the cell cycle in this highly interactive Click and Learn and find out how mutated versions of these proteins can lead to the development of cancer. Also available in Spanish.

  • Animated Life: Seeing the Invisible

    Animated Life: Seeing the Invisible

    Animated Shorts

    (6 min 31 sec) This animated feature celebrates 17th-century citizen-scientist Antonie van Leeuwenhoek, whose discoveries of microbes changed our view of the biological world. Also available in Spanish.

  • Autism and the Structure and Function of Synapses

    Autism and the Structure and Function of Synapses

    Animations

    (2 min 3 sec) Genes associated with autism affect the structure and function of neuronal synapses.

  • From Cancer Genomics to Cancer Drugs

    From Cancer Genomics to Cancer Drugs

    Science Talks

    (58 min 46 sec) Genetic data from a large number of tumor types reveal commonly mutated genes and uncover connections between different types of cancer.

  • Cancer As a Genetic Disease

    Cancer As a Genetic Disease

    Science Talks

    (58 min 33 sec) Understanding that cancer is caused by mutations in genes that regulate cell proliferation has led to the development of targeted drug therapies.

  • Gleevec-Resistant Form of Kinase BCR-ABL

    Gleevec-Resistant Form of Kinase BCR-ABL

    Animations

    (2 min 14 sec) Mutations in the BCR-ABL gene can cause resistance to Gleevec, but another drug, dasatinib, can be used instead.

  • Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Animations

    (3 min 31 sec) The drug Gleevec binds to and inactivates BCR-ABL, a mutant kinase that causes chronic myeloid leukemia. 

  • Cloning an Army of T Cells for Immune Defense

    Cloning an Army of T Cells for Immune Defense

    Animations

    (4 min 21 sec) View the animation to see how one type of immune cell—the helper T cell—interprets a message presented at the surface of the cell membrane. The message is an antigen, a protein fragment taken from an invading microbe. A series of events unfolds that results in the production of many clones of the helper T cell. These identical T cells can serve as a brigade forming an essential communication network to activate B cells, which make antibodies that will specifically attack the activating antigen.

  • Biochemistry and Cell Signaling Pathway of the Mc1r Gene

    Biochemistry and Cell Signaling Pathway of the Mc1r Gene

    Activities

    An advanced lesson that requires students to analyze partial DNA sequences of the Mc1r gene and identify the effects of mutations on the MC1R protein pathway.

  • Bacterial Quorum Sensing

    Bacterial Quorum Sensing

    Click & Learn

    Understand how quorum sensing works by reasoning through experiments involving genetically-engineered bioluminescent bacteria.

  • Symbiotic Bioluminescence

    Symbiotic Bioluminescence

    Click & Learn

    Explore the biology of the symbiotic relationship between the Hawaiian Bobtail squid and bioluminescent bacteria Vibrio fischeri.

  • Demonstration: Glowing bacteria in a flask

    Demonstration: Glowing bacteria in a flask

    Clips

    (52 sec) Dr. Bassler demonstrates the bioluminescence of a culture of Vibrio harveyi.

  • The LUX operon controls light production

    The LUX operon controls light production

    Animations

    (2 min 25 sec) A single transcription factor controls this operon, which contains five genes necessary to produce bioluminescence.

  • Prialt blocks motor synapse in fish

    Prialt blocks motor synapse in fish

    Animations

    (2 min 31 sec) Prialt, a drug derived from cone snail venom, paralyzes fish by blocking calcium channels at a motor synapse.

  • Electrical Activity of Neurons

    Electrical Activity of Neurons

    Click & Learn

    Measuring neuronal activity, generating action potentials, and recording the firing of individual neurons.

  • Demo: SHH concentration and eye position

    Demo: SHH concentration and eye position

    Clips

    (1 min 22 sec) A reduction in the level of sonic hedgehog (SHH) gene expression can lead to cyclopia.

  • Demo: Electrical measurement of muscle activity

    Demo: Electrical measurement of muscle activity

    Clips

    (2 min 10 sec) A live recording of muscle activity from Dr. Jessell's biceps and triceps muscles.

  • Molecular Mechanism of Synaptic Function

    Molecular Mechanism of Synaptic Function

    Animations

    (1 min 9 sec) Electrical and chemical signals are used by neurons to communicate with one another at contact points called synapses. Also available in Spanish.

  • Signal molecules trigger transcription factors

    Signal molecules trigger transcription factors

    Animations

    (2 min 4 sec) Varying concentrations of a signaling molecule activate different transcription factors and determine cell fate.

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