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  • Living Together

    Living Together

    Phenomenal Image

    Students explore photos of bobtail squid as an anchoring phenomenon to explore symbiosis and species interactions.

  • The Eukaryotic Cell Cycle and Cancer

    The Eukaryotic Cell Cycle and Cancer

    Click & Learn

    Explore the phases, checkpoints, and protein regulators of the cell cycle in this highly interactive Click and Learn and find out how mutated versions of these proteins can lead to the development of cancer. Also available in Spanish.

  • Animated Life: Seeing the Invisible

    Animated Life: Seeing the Invisible

    Animated Short

    (6 min 31 sec) This animated feature celebrates 17th-century citizen-scientist Antonie van Leeuwenhoek, whose discoveries of microbes changed our view of the biological world. Also available in Spanish.

  • Autism and the Structure and Function of Synapses

    Autism and the Structure and Function of Synapses

    Animation

    (2 min 3 sec) Genes associated with autism affect the structure and function of neuronal synapses.

  • From Cancer Genomics to Cancer Drugs

    From Cancer Genomics to Cancer Drugs

    Lecture

    (58 min 46 sec) Genetic data from a large number of tumor types reveal commonly mutated genes and uncover connections between different types of cancer.

  • Cancer As a Genetic Disease

    Cancer As a Genetic Disease

    Lecture

    (58 min 33 sec) Understanding that cancer is caused by mutations in genes that regulate cell proliferation has led to the development of targeted drug therapies.

  • Gleevec-Resistant Form of Kinase BCR-ABL

    Gleevec-Resistant Form of Kinase BCR-ABL

    Animation

    (2 min 14 sec) Mutations in the BCR-ABL gene can cause resistance to Gleevec, but another drug, dasatinib, can be used instead.

  • Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Gleevec Inhibits Cancer-Causing Kinase BCR-ABL

    Animation

    (3 min 31 sec) The drug Gleevec binds to and inactivates BCR-ABL, a mutant kinase that causes chronic myeloid leukemia. 

  • Cloning an Army of T Cells for Immune Defense

    Cloning an Army of T Cells for Immune Defense

    Animation

    (4 min 21 sec) View the animation to see how one type of immune cell—the helper T cell—interprets a message presented at the surface of the cell membrane. The message is an antigen, a protein fragment taken from an invading microbe. A series of events unfolds that results in the production of many clones of the helper T cell. These identical T cells can serve as a brigade forming an essential communication network to activate B cells, which make antibodies that will specifically attack the activating antigen.

  • Biochemistry and Cell Signaling Pathway of the Mc1r Gene

    Biochemistry and Cell Signaling Pathway of the Mc1r Gene

    Activity

    An advanced lesson that requires students to analyze partial DNA sequences of the Mc1r gene and identify the effects of mutations on the MC1R protein pathway.

  • Bacterial Quorum Sensing

    Bacterial Quorum Sensing

    Click & Learn

    Understand how quorum sensing works by reasoning through experiments involving genetically-engineered bioluminescent bacteria.

  • Symbiotic Bioluminescence

    Symbiotic Bioluminescence

    Click & Learn

    Explore the biology of the symbiotic relationship between the Hawaiian Bobtail squid and bioluminescent bacteria Vibrio fischeri.

  • Q&A on Quorum Sensing

    Q&A on Quorum Sensing

    Lecture

    (12 min 59 sec) In this 13-minute Q&A session, Dr. Bonnie Bassler answers questions on quorum sensing and other topics related to bacteria.

  • Eavesdropping on Tiny Conspiracies

    Eavesdropping on Tiny Conspiracies

    Lecture

    (58 min 29 sec) The quorum sensing system is a target for a new class of drugs that interfere with virulence without killing bacteria.

  • Biodiversity at a Snail's Pace

    Biodiversity at a Snail's Pace

    Lecture

    (58 min 29 sec) Cone snails have evolved many different toxins for different uses. Total molecular biodiversity may number in the millions.

  • Shedding Light on an Invisible World

    Shedding Light on an Invisible World

    Lecture

    (58 min 29 sec) Bacteria are capable of communicating and coordinating their activities with a molecular signaling system called quorum sensing.

  • From Venoms to Drugs

    From Venoms to Drugs

    Lecture

    (58 min 29 sec) Venomous carniverous cone snails are a rich source of molecules for scientific research and potential drug development.

  • Exploring Biodiversity: The Search for New Medicines

    Exploring Biodiversity: The Search for New Medicines

    Lecture

    What medical secrets do venomous snails hold? How can listening in on bacterial conversations help develop new antibiotics? In four presentations, Dr. Bonnie L. Bassler and Dr. Baldomero M. Olivera reveal how a deeper understanding of nature and biodiversity informs their research into new medicines.

  • Demonstration: Quorum sensing molecules

    Demonstration: Quorum sensing molecules

    Clip

    (50 sec) Quorum sensing signal molecules have parts that are common between species as well as species-specific parts.

  • Demonstration: Glowing bacteria in a flask

    Demonstration: Glowing bacteria in a flask

    Clip

    (52 sec) Dr. Bassler demonstrates the bioluminescence of a culture of Vibrio harveyi.

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