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Showing 1-13 of 13 Resources
  • Dante's Story

    Dante's Story

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    (6 min 6 sec) Dante is a 10-year-old boy born with hemimegalencephaly—an enlargement of half his brain.

  • The Search for Genetic Mutations that Cause Autism

    The Search for Genetic Mutations that Cause Autism

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    (2 min 5 sec) Dr. Christopher Walsh discusses how genomic science has made enormous contributions to our understanding of the genetic causes of autism.

  • Meet Dante—A Young Boy with Hemimegalencephaly

    Meet Dante—A Young Boy with Hemimegalencephaly

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    (2 min 33 sec) Dante is a healthy 10-year-old boy who has had half his cerebral cortex surgically removed to treat his seizures.

  • Meet Chris Walsh

    Meet Chris Walsh

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    (2 min 3 sec) Dr. Walsh is an HHMI investigator whose research focuses on understanding the genes involved in the development and function of the human brain.

  • Demo: SHH concentration and eye position

    Demo: SHH concentration and eye position

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    (1 min 22 sec) A reduction in the level of sonic hedgehog (SHH) gene expression can lead to cyclopia.

  • Long-distance neuronal path-finding

    Long-distance neuronal path-finding

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    (31 sec) Retinal axons travel across the brain, reading navigation cues, to find appropriate targets.

  • Growth cones in action

    Growth cones in action

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    (34 sec) The growth cones of two neurons sense and interact with one another.

  • Contact repulsion of a growth cone

    Contact repulsion of a growth cone

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    (1 min 5 sec) A growth cone contacts a repellant molecule on another axon, collapses, and withdraws.

  • Rett Syndrome

    Rett Syndrome

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    (2 min 52 sec) Dr. Zoghbi introduces the topic of Rett syndrome by showing how development usually progresses in a young girl. She then shows an excerpt from Silent Angels, introduced by Julia Roberts, which shows how Rett syndrome affects development.

  • Sperm Motility

    Sperm Motility

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    (21 sec) Video microscopy of sperm motility in an average human male and an infertile male.

  • Intracytoplasmic Sperm Injection (ICSI)

    Intracytoplasmic Sperm Injection (ICSI)

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    (1 min 16 sec) Video microscopy demonstrating how sperm from an infertile male can be injected into a female egg.

  • From Fertilization to Egg Laying in C. elegans

    From Fertilization to Egg Laying in C. elegans

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    (1 min 12 sec) Video of the fertilization of the C. elegans oocyte, the fusion of the egg and sperm nuclei, and the egg laying.

  • Embryonic Cell Division in C. elegans

    Embryonic Cell Division in C. elegans

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    (1 min 31 sec) Time-lapse microscopy showing cell division from 1 to 2 to 4 cell stages in C. elegans with fluorescent chromosomes.