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Showing 1-100 of 210 Resources
  • Great Transitions Interactive: Human Origins

    Great Transitions Interactive: Human Origins

    Click & Learn

    Examine fossil skeletons and footprints of early humans and compare them to skeletons of modern humans and chimpanzees to discover how different traits have evolved over time.

  • Sex Verification Testing of Athletes

    Sex Verification Testing of Athletes

    Click & Learn

    This interactive explores the biology of sex determination and development in humans, set against the backdrop of the different sex testing policies implemented throughout sports history.

  • Age Structure of Ebola Outbreaks

    Age Structure of Ebola Outbreaks

    Data Points

    Scientists analyzed demographics, including sex and age, of the spread of the Ebola Virus Disease during seven outbreaks in the Democratic Republic of Congo.

  • Fecal Microbiota Transplants: The Ins and Outs of FMT

    Fecal Microbiota Transplants: The Ins and Outs of FMT

    Feature Films

    (7 min 21 sec) Poop. You flush it, and usually that’s the end of the story. But to scientists like Mark Smith, poop is more than just waste – it’s medicine.

  • Microbes from Mom — Vaginal Birth vs C-Section

    Microbes from Mom — Vaginal Birth vs C-Section

    Feature Films

    (9 min 13 sec) Do you remember your first birthday present? No? Good, because it’s gross.

  • 3D Scan of Tiktaalik Fossil – Humerus

    3D Scan of Tiktaalik Fossil – Humerus

    3D Models

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil – Pelvis

    3D Scan of Tiktaalik Fossil – Pelvis

    3D Models

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil – Pectoral Fin

    3D Scan of Tiktaalik Fossil – Pectoral Fin

    3D Models

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil –  Body

    3D Scan of Tiktaalik Fossil – Body

    3D Models

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil –  Skull

    3D Scan of Tiktaalik Fossil – Skull

    3D Models

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • Monkey Social Status and Immune Response

    Monkey Social Status and Immune Response

    Data Points

    Scientists studied how the dominance ranking of female rhesus macaques living in social groups affected the expression of genes linked to immune response

  • Nature’s Cutest Symbiosis: The Bobtail Squid

    Nature’s Cutest Symbiosis: The Bobtail Squid

    Feature Films

    (8 min 5 sec) The bobtail squid is an underwater delicacy for many predators, so the creature found a handy superpower to stay alive: Invisibility

  • Maternal Microbiota Impacts Offspring Immune System

    Maternal Microbiota Impacts Offspring Immune System

    Data Points

    In this study, scientists compared two populations of pregnant mice, one which was kept germ-free throughout pregnancy and the other which was exposed during pregnancy to a strain of E. coli to determine whether the immune systems of offspring begin to develop in utero.

  • A Wasp Mom’s Gift: Blankets of Bacteria

    A Wasp Mom’s Gift: Blankets of Bacteria

    Feature Films

    (9 min 10 sec) You don’t want to be a honeybee when the beewolf is on the prowl.

  • Mosquitoes Might SAVE Lives, Thanks To Bacteria

    Mosquitoes Might SAVE Lives, Thanks To Bacteria

    Feature Films

    (9 min 4 sec) Dengue fever is a deadly mosquito-borne virus that plagues the earth, but science is inching closer to an unlikely solution: bacteria.

  • Superbugs That Resist Antibiotics Can Evolve in 11 Days

    Superbugs That Resist Antibiotics Can Evolve in 11 Days

    Feature Films

    (8 min 50 sec) Antibiotics like penicillin have a critical role in medicine, but using them is not a decision to be taken lightly.

  • Termites Digest Wood Thanks To Microbes

    Termites Digest Wood Thanks To Microbes

    Feature Films

    (7 min 11 sec) The next time you spot a termite chomping down on wood, know that they’re not dining alone.

  • Identifying the Key Genes for Regeneration

    Identifying the Key Genes for Regeneration

    Scientists at Work

    (9 min 55 sec) Planarians have an amazing ability to regenerate lost tissues. In this video, scientists knock out two different genes in planaria to start to understand how the process works—and they generate animals with two heads and two tails!

  • Virus Hunters: Epidemiology of Nipah Virus

    Virus Hunters: Epidemiology of Nipah Virus

    Activities

    In this activity, students will be exploring cases of Nipah virus (NiV) infection as an epidemiologist would, by collecting evidence and making calculations and predictions, based on scientific data.

  • Benefits of Schools

    Benefits of Schools

    Phenomenal Images

    Students explore photos of animals in groups as anchoring phenomena to explore animal behavior concepts.

  • How Lizards Find Their Way Home

    How Lizards Find Their Way Home

    Scientists at Work

    (8 min 33 sec) When Dr. Manuel Leal removed lizards from an area in the forest, he noticed an interesting phenomenon: all the lizards seemed to be back the next day. Watch as he sets up an experiment to study how these lizards navigate home. Also available in Spanish.

  • Sleep Clears β-amyloid from the Brain

    Sleep Clears β-amyloid from the Brain

    Data Points

    The researchers in this study tested whether the rate of Aβ removal is higher during sleep using mice as model organisms.

  • Studying Elephant Communication

    Studying Elephant Communication

    Scientists at Work

    (6 min 43 sec) Elephants can communicate over long distances using low-frequency sounds that travel both in the air and through the ground. Scientists are studying whether elephants can “hear” and interpret these ground vibrations.

  • Viral Lysis and Budding

    Viral Lysis and Budding

    Activities

    This activity outlines two demonstrations that model how enveloped and nonenveloped viruses are released from infected cells.

  • HIV Protease Inhibitors

    HIV Protease Inhibitors

    Activities

    This demonstration models how the HIV protease enzyme functions and how its activity is blocked by a class of anti-HIV drugs.

  • HIV Life Cycle Activities

    HIV Life Cycle Activities

    Collection

    A collection of activities and demonstrations focusing on various aspects of the human immunodeficiency virus (HIV) life cycle. They are designed to be completed individually or as part of the series...

  • Viral DNA Integration

    Viral DNA Integration

    Activities

    In this hands-on activity, students model how a double-stranded DNA copy of the HIV genome is integrated into the host cell DNA.

  • HIV Reverse Transcription and AZT

    HIV Reverse Transcription and AZT

    Activities

    Students model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

  • HIV Receptors and Co-receptors

    HIV Receptors and Co-receptors

    Activities

    This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

  • Resource Guides

    Resource Guides

    Collection

    Designed by educators, BioInteractive’s resource guides will help you select BioInteractive resources aligned to specific topics and standards, including the AP® Biology Curriculum Framework.

  • Bat Echolocation

    Bat Echolocation

    Data Points

    In this study, researchers tested whether bats change their behavior while hunting based on feedback from echolocation.

  • Think Like a Scientist: Natural Selection in an Outbreak

    Think Like a Scientist: Natural Selection in an Outbreak

    Scientists at Work

    (7 min 29 sec) This video brings us to the front lines of the 2013–2015 Ebola outbreak in west Africa and explains how scientists monitored the evolution of the virus by analyzing its genome.

  • Genetic Mutations and Disease Interactive

    Genetic Mutations and Disease Interactive

    Click & Learn

    This interactive focuses on the roles of germline and somatic cell mutations in human disease. It supports the 2013 Holiday Lectures on Science, Medicine in the Genomic Era.

  • How Animals Use Sound to Communicate

    How Animals Use Sound to Communicate

    Click & Learn

    Using elephants, finches, bats, and moths, as case studies, explore different aspects of how animals use sound to communicate.

  • Patterns of Zoonotic Disease

    Patterns of Zoonotic Disease

    Data Points

    In this study, scientists analyzed previously published data on terrestrial mammal zoonotic host species and the pathogens they carry to search for global patterns of zoonotic disease distribution.

  • Understanding Variation

    Understanding Variation

    Activities

    This lesson complements the film The Biology of Skin Color and discusses variation in human skin color and polygenic inheritance. Also available in Spanish.

  • Zebrafish and Skin Color

    Zebrafish and Skin Color

    Activities

    This lesson complements the film The Biology of Skin Color and explores how experimental work in zebrafish led to a better understanding of the role of the gene SLC24A5 in human skin color.

  • Thermoregulation in Dinosaurs

    Thermoregulation in Dinosaurs

    Data Points

    Grady and colleagues compared dinosaur fossil evidence with evidence from living animal species to shed more light on the type of thermoregulation that dinosaurs used—ectothermy, endothermy, or mesothermy.

  • Virus Explorer

    Virus Explorer

    Click & Learn

    Explore the similarities and differences of a variety of viruses by sorting them based on structure, genomic make-up, host range, transmission mechanism, and vaccine availability.

  • Virus Hunter: Monitoring Nipah Virus in Bat Populations

    Virus Hunter: Monitoring Nipah Virus in Bat Populations

    Scientists at Work

    (9 min 1 sec) In this video we follow scientists working in Bangladesh as they test fruit bat populations to determine whether they are infected with Nipah virus—a potentially deadly virus when passed on to humans.

  • Alzheimer’s Disease: Piecing Together the Evidence

    Alzheimer’s Disease: Piecing Together the Evidence

    Click & Learn

    This interactive explores evidence from brain anatomy, tissue histology, and genetic studies to reveal possible targets for the treatment of Alzheimer’s disease.

  • Origin of a Gene Mutation Causing Early-Onset Alzheimer’s Disease

    Origin of a Gene Mutation Causing Early-Onset Alzheimer’s Disease

    Data Points

    A team of scientists built a pedigree of a large extended family in Antioquia, Colombia, that has a high prevalence of early-onset familial Alzheimer’s disease due to a mutation in the PSEN1 gene. Worksheets also available in Spanish.

  • Amylase Copy Number and Diet

    Amylase Copy Number and Diet

    Data Points

    A team of scientists investigated whether there is a correlation between the number of AMY1 gene copies and the type of diet (high-starch or low-starch) of a population.

  • WildCam Lab

    WildCam Lab

    Click & Learn

    The WildCam Lab is a part of WildCam Gorongosa, an online citizen science platform where users identify animals in trail camera photos. Using the WildCam Lab, students can investigate ecological questions and test hypotheses by exploring trail camera data using an interactive map. 

  • Lactase Film with Quiz

    Lactase Film with Quiz

    Interactive Videos

    (14 min 52 sec) Embedded quiz modules test students’ understanding as they watch a short film that explores the evolution of the ability to digest lactose as adults (lactose tolerance) and the genetic changes associated with the trait.

  • Skin Color Film with Quiz

    Skin Color Film with Quiz

    Interactive Videos

    (18 min 58 sec) Embedded quiz modules test students’ understanding as they watch a short film that explores the evidence for the evolution of the variation in skin color among human populations.

  • Mosquito-Borne Viral Diseases

    Mosquito-Borne Viral Diseases

    Collection

    Most of the viral diseases transmitted by mosquitoes are caused by RNA viruses. One group of RNA viruses, the flavivirus, includes yellow fever, dengue, West Nile, Japanese encephalitis, St. Louis...

  • Slug Power

    Slug Power

    Phenomenal Images

    Students explore photos of a sea slug and chloroplasts as anchoring phenomena to explore photosynthesis concepts.

  • Origin of Humans with Quiz

    Origin of Humans with Quiz

    Interactive Videos

    (19 min 44 sec) Embedded quiz modules test students’ understanding as they watch a short film on the major human fossil finds from Africa  and what they reveal about the history of our evolutionary origins.

  • Origin of Birds With Quiz

    Origin of Birds With Quiz

    Interactive Videos

    (18 min 59 sec) Embedded quiz modules test students’ understanding as they watch a short film about the evidence that showed birds descended from dinosaurs.

  • Genetic Origin of Variation in Human Skin Color

    Genetic Origin of Variation in Human Skin Color

    Data Points

    Dr. Rebecca Lamason and colleagues studied the genetic origin of variation in human skin color using a model organism, the zebrafish.

  • Comparative Anatomy of the Domestic Chicken

    Comparative Anatomy of the Domestic Chicken

    Click & Learn

    Trace the evolutionary history of birds by comparing the shapes and structures of certain bones in a chicken to those of some of its extinct and living relatives. Also available in Spanish.

  • Human Skin Color: Evidence for Selection

    Human Skin Color: Evidence for Selection

    Activities

    This case study is based on the short film The Biology of Skin Color. Students use real data to propose hypotheses, make predictions, and justify claims with evidence. Also available in Spanish.

  • The Origin of Flight: What Use Is Half a Wing?

    The Origin of Flight: What Use Is Half a Wing?

    Scientists at Work

    (8 min 16 sec) Biologist Ken Dial's study of how young birds use their developing wings sheds light on the evolution of flight in birds.

  • How We Get Our Skin Color Interactive

    How We Get Our Skin Color Interactive

    Interactive Videos

    (3 min 32 sec) This interactive animation about the biology of skin color provides stop points at which students can further explore the material through additional text and illustrations, videos, questions, and simple interactive widgets.

  • Film Guide for The Biology of Skin Color

    Film Guide for The Biology of Skin Color

    Film Guides

    The following classroom-ready resources complement The Biology of Skin Color. Featuring anthropologist Dr. Nina Jablonski, the film walks us through the evidence that differences in human skin color are adaptations to varying intensity of UV light. Also available in Spanish.

  • WildCam Gorongosa

    WildCam Gorongosa

    Click & Learn

    Researchers in Gorongosa National Park use remote trail cameras to study the park’s wildlife. You can contribute to this important research through WildCam Gorongosa, an online citizen science platform.

  • Schooling Behavior of Stickleback Fish from Different Habitats

    Schooling Behavior of Stickleback Fish from Different Habitats

    Data Points

    A team of scientists studied the schooling behavior of threespine stickleback fish by experimentally testing how individual fish responded to an artificial fish school model.

  • How Did Dinosaurs Regulate Their Body Temperature?

    How Did Dinosaurs Regulate Their Body Temperature?

    Activities

    This activity uses data from a 2014 scientific paper to explore thermoregulation in living and extinct animals, including dinosaurs. 

  • Organismal Biology

    Organismal Biology

    Collection

    Resources related to biology of organisms, including physiology, anatomy, infectious diseases, and developmental biology.

  • Great Transitions

    Great Transitions

    Collection

    Stunning fossil finds have revealed the fascinating stories of major transitions in the history of life on our planet—from fish that gained the land, to reptiles that took to the air, and primates...

  • Episode 3: Your Inner Monkey

    Episode 3: Your Inner Monkey

    Feature Films

    (54 min 51 sec) Join Neil Shubin as he links our hands, vision, and brains to ancient primate ancestors. PLEASE N​OTE: Due to international distribution restrictions, these programs can only be streamed in the United States and Canada.

  • Episode 2: Your Inner Reptile

    Episode 2: Your Inner Reptile

    Feature Films

    (54 min 41 sec) Join Neil Shubin as he links our hair, teeth and hearing to ancient reptilian ancestors. PLEASE N​OTE: Due to international distribution restrictions, these programs can only be streamed in the United States and Canada.

  • Episode 1: Your Inner Fish

    Episode 1: Your Inner Fish

    Feature Films

    (54 min 41 sec) See how the genetic legacy of a fish can be seen today in our own DNA. PLEASE N​OTE: Due to international distribution restrictions, these programs can only be streamed in the United States and Canada.

  • How We Get Our Skin Color

    How We Get Our Skin Color

    Animations

    (3 min 32 sec) This engaging animation shows how human skin cells produce the pigment melanin, which gives skin its color. 

  • The Biology of Skin Color

    The Biology of Skin Color

    Short Films

    (18 min 58 sec) Penn State University anthropologist Dr. Nina Jablonski walks us through the evidence that the different shades of skin color among human populations arose as adaptations to the intensity of ultraviolet radiation in different parts of the world. Also available in Spanish.

  • Icefish Film with Quiz

    Icefish Film with Quiz

    Interactive Videos

    (13 min 14 sec) Embedded quiz modules test students’ understanding as they watch the short film on the icefish—an example of how genes are reused and recycled.

  • Film Guides: The Origin of Humans

    Film Guides: The Origin of Humans

    Film Guides

    The following classroom-ready resources complement Great Transitions: The Origin of Humans, which reveals the history of our evolutionary origins. Also available in Spanish.

  • Great Transitions: The Origin of Birds

    Great Transitions: The Origin of Birds

    Short Films

    (18 min 59 sec) In the second film of the Great Transitions trilogy, paleontologist Julia Clarke takes us on a journey to uncover the evidence that birds descended from dinosaurs. Also available in Spanish.

  • The Lone Anole

    The Lone Anole

    Phenomenal Images

    Students explore a photo of an anole lizard as an anchoring phenomenon to explore adaptations and natural selection

  • Great Transitions: The Origin of Humans

    Great Transitions: The Origin of Humans

    Short Films

    (19 min 44 sec) Which traits distinguish humans from other primates? When and where did these traits evolve? Analysis of the major fossil finds from Africa, dating back to 4.4 million years ago, provides answers to these questions and reveals the history of our evolutionary origins. Also available in Spanish.

  • Vertebrate Circulatorium

    Vertebrate Circulatorium

    Click & Learn

    Compare and contrast the anatomy of the heart and the circulatory systems of major vertebrate groups and gain insights into their evolution.

  • Milk—How Sweet Is It?

    Milk—How Sweet Is It?

    Activities

    In this lab, students test different samples to see which ones contain the lactase enzyme. Also available in Spanish.

  • Pedigrees and the Inheritance of Lactose Intolerance

    Pedigrees and the Inheritance of Lactose Intolerance

    Activities

    Students explore the genetic changes associated with lactose tolerance/intolerance and how the trait is inherited in families. Also available in Spanish.

  • Holiday Lecture 2004 Update—Jeff Friedman

    Holiday Lecture 2004 Update—Jeff Friedman

    Clips

    (3 min 52 sec) HHMI investigator Jeff Friedman provides an update to his 2004 lectures on obesity.

  • West Nile Virus: Vectors and Hosts Game

    West Nile Virus: Vectors and Hosts Game

    Activities

    Play the West Nile virus game to learn how the virus spreads and how the outcome changes depending on the species that is infected. Resources are also available in Spanish.

  • Lizard Evolution Virtual Lab

    Lizard Evolution Virtual Lab

    Virtual Labs

    In the Lizard Evolution Virtual Lab students explore the evolution of the anole lizards in the Caribbean by collecting and analyzing their own data.  

  • Infectious Disease

    Infectious Disease

    Collection

    Engaging multimedia resources to teach about viruses, the immune systems, and infectious disease.

  • Neuroscience

    Neuroscience

    Collection

    A rich variety of videos, interactive modules, and animations to teach about the nervous system.

  • Rhinovirus

    Rhinovirus

    3D Models

    A 3D model of rhinovirus, an RNA genome virus that is the main cause of the common cold in humans.

  • Nodamura Virus

    Nodamura Virus

    3D Models

    A 3D model of nodamura virus.

  • Dengue Virus

    Dengue Virus

    3D Models

    A 3D model of dengue virus.

  • Dante's Story

    Dante's Story

    Clips

    (6 min 6 sec) Dante is a 10-year-old boy born with hemimegalencephaly—an enlargement of half his brain.

  • The Search for Genetic Mutations that Cause Autism

    The Search for Genetic Mutations that Cause Autism

    Clips

    (2 min 5 sec) Dr. Christopher Walsh discusses how genomic science has made enormous contributions to our understanding of the genetic causes of autism.

  • Meet Dante—A Young Boy with Hemimegalencephaly

    Meet Dante—A Young Boy with Hemimegalencephaly

    Clips

    (2 min 33 sec) Dante is a healthy 10-year-old boy who has had half his cerebral cortex surgically removed to treat his seizures.

  • CLARITY—Cutting Edge Microscopy for Brain Imaging

    CLARITY—Cutting Edge Microscopy for Brain Imaging

    Clips

    (1 min 17 sec) A new technique for making the brain transparent provides extremely detailed views of groups of neurons.

  • Cancer and Cell Fate in the Intestinal Epithelium

    Cancer and Cell Fate in the Intestinal Epithelium

    Animations

    (2 min 17 sec) Disrupting the normal processes of differentiation and maturation of the intestinal epithelial cells can lead to cancer. Also available in Spanish.

  • Autism and the Structure and Function of Synapses

    Autism and the Structure and Function of Synapses

    Animations

    (2 min 3 sec) Genes associated with autism affect the structure and function of neuronal synapses.

  • Development of the Cerebral Cortex

    Development of the Cerebral Cortex

    Animations

    (1 min 43 sec) Most of the neurons of the cerebral cortex arise from progenitor cells that undergo repeated cell division.

  • Film Guides: The Origin of Tetrapods

    Film Guides: The Origin of Tetrapods

    Film Guides

    The following classroom-ready resources complement Great Transitions: The Origin of Tetrapods, which tells the story of the discovery of Tiktaalik, a creature with features common to fish and four-legged animals, or tetrapods.

  • Beaks As Tools: Selective Advantage in Changing Environments

    Beaks As Tools: Selective Advantage in Changing Environments

    Activities

    This classroom experiment supports the film The Origin of Species: The Beak of the Finch. Students collect and analyze data to learn why even slight variations in beak size can make the difference between life and death.

  • Using DNA to Explore Lizard Phylogeny

    Using DNA to Explore Lizard Phylogeny

    Activities

    This activity supports the film The Origin of Species: Lizards in an Evolutionary Tree. Students are guided to sort the lizard species by appearance, then generate a phylogenetic tree using the lizards’ DNA sequences to evaluate whether species that appear similar are closely related to each other.

  • Great Transitions: The Origin of Tetrapods

    Great Transitions: The Origin of Tetrapods

    Short Films

    (17 min 11 sec) One of the most exciting discoveries in the long history of fossil exploration is Tiktaalik, a creature with a mix of features common to fish and four-legged animals, or tetrapods.

  • Explore Your Inner Animals

    Explore Your Inner Animals

    Click & Learn

    This interactive explores different anatomical features of the human body and what they reveal about the evolutionary history we share with other organisms, including earlier, long-extinct species.

  • Genomic Medicine, Autism, and Cancer

    Genomic Medicine, Autism, and Cancer

    Science Talks

    (37 min 26 sec) A student discussion with the lecturers of the 2013 Holiday Lectures on Science.

  • From Cancer Genomics to Cancer Drugs

    From Cancer Genomics to Cancer Drugs

    Science Talks

    (58 min 46 sec) Genetic data from a large number of tumor types reveal commonly mutated genes and uncover connections between different types of cancer.

  • Decoding the Autism Puzzle

    Decoding the Autism Puzzle

    Science Talks

    (58 min 5 sec) Over the past decade, the application of advanced DNA sequencing techniques has greatly increased our understanding of the genetic basis of autism.

  • Sizing Up the Brain Gene By Gene

    Sizing Up the Brain Gene By Gene

    Science Talks

    (59 min 32 sec) Recent advances in DNA sequencing technology have led to a better understanding of the many genes that play a role in brain development.

  • Anole Lizards: An Example of Speciation

    Anole Lizards: An Example of Speciation

    Animations

    (2 min 38 sec) This animation features the anole lizards as an example of how a single species can split and multiply into many different species with distinct traits.

  • Film Guides: The Origin of Species: Lizards in an Evolutionary Tree

    Film Guides: The Origin of Species: Lizards in an Evolutionary Tree

    Film Guides

    The following classroom-ready resources complement The Origin of Species: Lizards in an Evolutionary Tree. Research on the anole lizards is enriching our understanding of evolutionary processes, such as adaptation by natural selection, convergent evolution, and the formation of new species. Also available in Spanish.

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