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From Cancer Genomics to Cancer Drugs

Science Talks

(58 min 46 sec) Genetic data from a large number of tumor types reveal commonly mutated genes and uncover connections between different types of cancer.
Cloning an Army of T Cells for Immune Defense

Animations

(4 min 21 sec) View the animation to see how one type of immune cell—the helper T cell—interprets a message presented at the surface of the cell membrane. The message is an antigen, a protein fragment taken from an invading microbe. A series of events unfolds that results in the production of many clones of the helper T cell. These identical T cells can serve as a brigade forming an essential communication network to activate B cells, which make antibodies that will specifically attack the activating antigen.
CTL killing a target cell

Clips

(1 min 17 sec) Video microscopy of a cytotoxic T lymphocyte in action.
Antigen presentation and CTL

Animations

(2 min 34 sec) How a cell infected by a virus signals cytotoxic T lymphocytes to kill the cell before the virus replicates and spreads.

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