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  • Sex Verification Testing of Athletes

    Sex Verification Testing of Athletes

    Click & Learn

    This interactive explores the biology of sex determination and development in humans, set against the backdrop of the different sex testing policies implemented throughout sports history.

  • Teacher Guides

    Teacher Guides

    Collection

    Designed by educators, BioInteractive’s teacher guides will help you select BioInteractive resources aligned to specific topics and standards, including the AP® Biology Curriculum Framework.

  • Understanding Variation

    Understanding Variation

    Activity

    This lesson complements the film The Biology of Skin Color and discusses variation in human skin color and polygenic inheritance. Also available in Spanish.

  • Zebrafish and Skin Color

    Zebrafish and Skin Color

    Activity

    This lesson complements the film The Biology of Skin Color and explores how experimental work in zebrafish led to a better understanding of the role of the gene SLC24A5 in human skin color.

  • Skin Color Interactive Video

    Skin Color Interactive Video

    Interactive Video

    (18 min 58 sec) Embedded quiz modules test students’ understanding as they watch a short film that explores the evidence for the evolution of the variation in skin color among human populations.

  • Film Guide for The Biology of Skin Color

    Film Guide for The Biology of Skin Color

    Film Guide

    The following classroom-ready resources complement The Biology of Skin Color. Featuring anthropologist Dr. Nina Jablonski, the film walks us through the evidence that differences in human skin color are adaptations to varying intensity of UV light. Also available in Spanish.

  • The Biology of Skin Color

    The Biology of Skin Color

    Short Film

    (18 min 58 sec) Penn State University anthropologist Dr. Nina Jablonski walks us through the evidence that the different shades of skin color among human populations arose as adaptations to the intensity of ultraviolet radiation in different parts of the world. Also available in Spanish.

  • Icefish Film with Quiz

    Icefish Film with Quiz

    Interactive Video

    (13 min 14 sec) Embedded quiz modules test students’ understanding as they watch the short film on the icefish—an example of how genes are reused and recycled.

  • Pedigrees and the Inheritance of Lactose Intolerance

    Pedigrees and the Inheritance of Lactose Intolerance

    Activity

    Students explore the genetic changes associated with lactose tolerance/intolerance and how the trait is inherited in families. Also available in Spanish.

  • Using DNA to Explore Lizard Phylogeny

    Using DNA to Explore Lizard Phylogeny

    Activity

    This activity supports the film The Origin of Species: Lizards in an Evolutionary Tree. Students are guided to sort the lizard species by appearance, then generate a phylogenetic tree using the lizards’ DNA sequences to evaluate whether species that appear similar are closely related to each other.

  • The Origin of Species: Lizards in an Evolutionary Tree

    The Origin of Species: Lizards in an Evolutionary Tree

    Short Film

    (17 min 45 sec) In the Caribbean islands, adaptation to several common habitats has led to a large adaptive radiation with interesting examples of convergent evolution. Also available in Spanish.

  • The Making of the Fittest: The Birth and Death of Genes

    The Making of the Fittest: The Birth and Death of Genes

    Short Film

    (13 min 10 sec) Scientists have pieced together the evolutionary history of the Antarctic icefish. The icefish makes an excellent case study for genetic evolution as both the gain and loss of genes have led to key adaptations.

  • Film Guides: The Birth and Death of Genes

    Film Guides: The Birth and Death of Genes

    Film Guide

    The following classroom-ready resources complement The Making of the Fittest: The Birth and Death of Genes, which describes how scientists have pieced together the evolutionary history of the Antarctic icefish. The icefish makes an excellent case study for genetic evolution as both the gain and loss of genes have led to key adaptations.

  • Molecular Genetics of Color Mutations in Rock Pocket Mice

    Molecular Genetics of Color Mutations in Rock Pocket Mice

    Activity

    A lesson that requires students to transcribe and translate portions of the wild-type and mutant rock pocket mouse Mc1r genes and compare sequences to identify the locations and types of mutations responsible for the coat color variation described in the film. Also available in Spanish.

  • The Virus Hunter's Toolkit

    The Virus Hunter's Toolkit

    Lecture

    (58 min 33 sec) New technologies like the Virochip harness DNA's properties to identify and fight new viruses.

  • Viral Outbreak: The Science of Emerging Disease

    Viral Outbreak: The Science of Emerging Disease

    Lecture

    Watch two leading virus researchers explain how they use both simple and sophisticated technologies to detect and fight infectious agents.

  • Mutant mice with crossed excitation hop

    Mutant mice with crossed excitation hop

    Clip

    (1 min 18 sec) Kangaroo-like hopping when spinal cord excitatory interneurons cross the midline to stimulate both sides.

  • Sickle Cell Anemia

    Sickle Cell Anemia

    Animation

    (1 min) Sickle cell anemia is a genetic disease that affects hemoglobin.

  • Test Your Knowledge of Sex Determination

    Test Your Knowledge of Sex Determination

    Click & Learn

    Answer the questions in this online quiz to test your knowledge of what determines the sex of a human, a fruit fly, and a snapping turtle.

  • Meiosis

    Meiosis

    Animation

    (5 min 53 sec) Meiosis, the form of cell division unique to egg and sperm production, sets the stage for sex determination by creating sperm that carry either an X or a Y sex chromosome. But what is it about the X or Y that determines sex? Also available in Spanish.

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