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Showing 1-80 of 83 Resources
  • Why Two Heads?

    Why Two Heads?

    Phenomenal Images

    Students explore images of planarians regenerating body parts as phenomena to explore cell division and differentiation.

  • Great Transitions Interactive: Human Origins

    Great Transitions Interactive: Human Origins

    Click & Learn

    Examine fossil skeletons and footprints of early humans and compare them to skeletons of modern humans and chimpanzees to discover how different traits have evolved over time.

  • Sex Verification Testing of Athletes

    Sex Verification Testing of Athletes

    Click & Learn

    This interactive explores the biology of sex determination and development in humans, set against the backdrop of the different sex testing policies implemented throughout sports history.

  • Age Structure of Ebola Outbreaks

    Age Structure of Ebola Outbreaks

    Data Points

    Scientists analyzed demographics, including sex and age, of the spread of the Ebola Virus Disease during seven outbreaks in the Democratic Republic of Congo.

  • 3D Scan of Tiktaalik Fossil – Humerus

    3D Scan of Tiktaalik Fossil – Humerus

    3D Models

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil – Pelvis

    3D Scan of Tiktaalik Fossil – Pelvis

    3D Models

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil – Pectoral Fin

    3D Scan of Tiktaalik Fossil – Pectoral Fin

    3D Models

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil –  Body

    3D Scan of Tiktaalik Fossil – Body

    3D Models

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • 3D Scan of Tiktaalik Fossil –  Skull

    3D Scan of Tiktaalik Fossil – Skull

    3D Models

    3D-scans of fossil bones of Tiktaalik, a creature with a mix of features common to fish and tetrapods.

  • Monkey Social Status and Immune Response

    Monkey Social Status and Immune Response

    Data Points

    Scientists studied how the dominance ranking of female rhesus macaques living in social groups affected the expression of genes linked to immune response.

  • Maternal Microbiota Impacts Offspring Immune System

    Maternal Microbiota Impacts Offspring Immune System

    Data Points

    In this study, scientists compared two populations of pregnant mice, one which was kept germ-free throughout pregnancy and the other which was exposed during pregnancy to a strain of E. coli to determine whether the immune systems of offspring begin to develop in utero. Worksheets also available in Spanish.

  • Termites Digest Wood Thanks To Microbes

    Termites Digest Wood Thanks To Microbes

    Animated Shorts

    (7 min 11 sec) The next time you spot a termite chomping down on wood, know that they’re not dining alone.

  • Identifying the Key Genes for Regeneration

    Identifying the Key Genes for Regeneration

    Scientists at Work

    (9 min 55 sec) Planarians have an amazing ability to regenerate lost tissues. In this video, scientists knock out two different genes in planaria to start to understand how the process works—and they generate animals with two heads and two tails!

  • Benefits of Schools

    Benefits of Schools

    Phenomenal Images

    Students explore photos of animals in groups as phenomena to explore animal behavior concepts.

  • How Lizards Find Their Way Home

    How Lizards Find Their Way Home

    Scientists at Work

    (8 min 33 sec) When Dr. Manuel Leal removed lizards from an area in the forest, he noticed an interesting phenomenon: all the lizards seemed to be back the next day. Watch as he sets up an experiment to study how these lizards navigate home. Also available in Spanish.

  • Sleep Clears β-amyloid from the Brain

    Sleep Clears β-amyloid from the Brain

    Data Points

    The researchers in this study tested whether the rate of Aβ removal is higher during sleep using mice as model organisms. Worksheets also available in Spanish.

  • Studying Elephant Communication

    Studying Elephant Communication

    Scientists at Work

    (6 min 43 sec) Elephants can communicate over long distances using low-frequency sounds that travel both in the air and through the ground. Scientists are studying whether elephants can “hear” and interpret these ground vibrations.

  • Viral Lysis and Budding

    Viral Lysis and Budding

    Labs & Demos

    This activity outlines two demonstrations that model how enveloped and nonenveloped viruses are released from infected cells.

  • HIV Protease Inhibitors

    HIV Protease Inhibitors

    Labs & Demos

    This demonstration models how the HIV protease enzyme functions and how its activity is blocked by a class of anti-HIV drugs.

  • Viral DNA Integration

    Viral DNA Integration

    Labs & Demos

    In this hands-on activity, students model how a double-stranded DNA copy of the HIV genome is integrated into the host cell DNA.

  • HIV Reverse Transcription and AZT

    HIV Reverse Transcription and AZT

    Card Activities

    Students model how the anti-HIV drug AZT (azidothymidine) interferes with the process of viral replication.

  • HIV Receptors and Co-receptors

    HIV Receptors and Co-receptors

    Labs & Demos

    This demonstration models the first step of the HIV life cycle: the binding of HIV envelope proteins to receptors on human helper T cells.

  • Bat Echolocation

    Bat Echolocation

    Data Points

    In this study, researchers tested whether bats change their behavior while hunting based on feedback from echolocation.

  • Think Like a Scientist: Natural Selection in an Outbreak

    Think Like a Scientist: Natural Selection in an Outbreak

    Scientists at Work

    (7 min 29 sec) This video brings us to the front lines of the 2013–2015 Ebola outbreak in west Africa and explains how scientists monitored the evolution of the virus by analyzing its genome.

  • How Animals Use Sound to Communicate

    How Animals Use Sound to Communicate

    Click & Learn

    Using elephants, finches, bats, and moths, as case studies, explore different aspects of how animals use sound to communicate.

  • Patterns of Zoonotic Disease

    Patterns of Zoonotic Disease

    Data Points

    In this study, scientists analyzed previously published data on terrestrial mammal zoonotic host species and the pathogens they carry to search for global patterns of zoonotic disease distribution.

  • Understanding Variation

    Understanding Variation

    Lessons

    This lesson complements the film The Biology of Skin Color and discusses variation in human skin color and polygenic inheritance. Also available in Spanish.

  • Thermoregulation in Dinosaurs

    Thermoregulation in Dinosaurs

    Data Points

    Grady and colleagues compared dinosaur fossil evidence with evidence from living animal species to shed more light on the type of thermoregulation that dinosaurs used—ectothermy, endothermy, or mesothermy.

  • Virus Explorer

    Virus Explorer

    Click & Learn

    Explore the similarities and differences of a variety of viruses by sorting them based on structure, genomic make-up, host range, transmission mechanism, and vaccine availability.

  • Virus Hunter: Monitoring Nipah Virus in Bat Populations

    Virus Hunter: Monitoring Nipah Virus in Bat Populations

    Scientists at Work

    (9 min 1 sec) In this video we follow scientists working in Bangladesh as they test fruit bat populations to determine whether they are infected with Nipah virus—a potentially deadly virus when passed on to humans.

  • Alzheimer’s Disease: Piecing Together the Evidence

    Alzheimer’s Disease: Piecing Together the Evidence

    Click & Learn

    This interactive explores evidence from brain anatomy, tissue histology, and genetic studies to reveal possible targets for the treatment of Alzheimer’s disease.

  • Origin of a Gene Mutation Causing Early-Onset Alzheimer’s Disease

    Origin of a Gene Mutation Causing Early-Onset Alzheimer’s Disease

    Data Points

    A team of scientists built a pedigree of a large extended family in Antioquia, Colombia, that has a high prevalence of early-onset familial Alzheimer’s disease due to a mutation in the PSEN1 gene. Worksheets also available in Spanish.

  • Amylase Copy Number and Diet

    Amylase Copy Number and Diet

    Data Points

    A team of scientists investigated whether there is a correlation between the number of AMY1 gene copies and the type of diet (high-starch or low-starch) of a population.

  • Origin of Birds With Quiz

    Origin of Birds With Quiz

    Interactive Videos

    (18 min 59 sec) Embedded quiz modules test students’ understanding as they watch a short film about the evidence that showed birds descended from dinosaurs.

  • Genetic Origin of Variation in Human Skin Color

    Genetic Origin of Variation in Human Skin Color

    Data Points

    Dr. Rebecca Lamason and colleagues studied the genetic origin of variation in human skin color using a model organism, the zebrafish.

  • Comparative Anatomy of the Domestic Chicken

    Comparative Anatomy of the Domestic Chicken

    Click & Learn

    Trace the evolutionary history of birds by comparing the shapes and structures of certain bones in a chicken to those of some of its extinct and living relatives. Also available in Spanish.

  • Human Skin Color: Evidence for Selection

    Human Skin Color: Evidence for Selection

    Case Studies

    This case study is based on the short film The Biology of Skin Color. Students use real data to propose hypotheses, make predictions, and justify claims with evidence. Also available in Spanish.

  • The Origin of Flight: What Use Is Half a Wing?

    The Origin of Flight: What Use Is Half a Wing?

    Scientists at Work

    (8 min 16 sec) Biologist Ken Dial's study of how young birds use their developing wings sheds light on the evolution of flight in birds.

  • How We Get Our Skin Color Interactive

    How We Get Our Skin Color Interactive

    Interactive Videos

    (3 min 32 sec) This interactive animation about the biology of skin color provides stop points at which students can further explore the material through additional text and illustrations, videos, questions, and simple interactive widgets.

  • Film Guide for The Biology of Skin Color

    Film Guide for The Biology of Skin Color

    Film Guides

    The following classroom-ready resources complement The Biology of Skin Color. Featuring anthropologist Dr. Nina Jablonski, the film walks us through the evidence that differences in human skin color are adaptations to varying intensity of UV light. Also available in Spanish.

  • Schooling Behavior of Stickleback Fish from Different Habitats

    Schooling Behavior of Stickleback Fish from Different Habitats

    Data Points

    A team of scientists studied the schooling behavior of threespine stickleback fish by experimentally testing how individual fish responded to an artificial fish school model.

  • How Did Dinosaurs Regulate Their Body Temperature?

    How Did Dinosaurs Regulate Their Body Temperature?

    Lessons

    This activity uses data from a 2014 scientific paper to explore thermoregulation in living and extinct animals, including dinosaurs. 

  • Episode 3: Your Inner Monkey

    Episode 3: Your Inner Monkey

    Feature Films

    (54 min 51 sec) Join Neil Shubin as he links our hands, vision, and brains to ancient primate ancestors. PLEASE N​OTE: Due to international distribution restrictions, these programs can only be streamed in the United States and Canada.

  • Episode 2: Your Inner Reptile

    Episode 2: Your Inner Reptile

    Feature Films

    (54 min 41 sec) Join Neil Shubin as he links our hair, teeth and hearing to ancient reptilian ancestors. PLEASE N​OTE: Due to international distribution restrictions, these programs can only be streamed in the United States and Canada.

  • Episode 1: Your Inner Fish

    Episode 1: Your Inner Fish

    Feature Films

    (54 min 41 sec) See how the genetic legacy of a fish can be seen today in our own DNA. PLEASE N​OTE: Due to international distribution restrictions, these programs can only be streamed in the United States and Canada.

  • How We Get Our Skin Color

    How We Get Our Skin Color

    Animations

    (3 min 32 sec) This engaging animation shows how human skin cells produce the pigment melanin, which gives skin its color. 

  • The Biology of Skin Color

    The Biology of Skin Color

    Short Films

    (18 min 58 sec) Penn State University anthropologist Dr. Nina Jablonski walks us through the evidence that the different shades of skin color among human populations arose as adaptations to the intensity of ultraviolet radiation in different parts of the world. Also available in Spanish.

  • Film Guides: The Origin of Humans

    Film Guides: The Origin of Humans

    Film Guides

    The following classroom-ready resources complement Great Transitions: The Origin of Humans, which reveals the history of our evolutionary origins. Also available in Spanish.

  • The Lone Anole

    The Lone Anole

    Phenomenal Images

    Students explore a photo of an anole lizard as a phenomenon to explore adaptations and natural selection.

  • Milk—How Sweet Is It?

    Milk—How Sweet Is It?

    Labs & Demos

    In this lab, students test different samples to see which ones contain the lactase enzyme. Also available in Spanish.

  • Pedigrees and the Inheritance of Lactose Intolerance

    Pedigrees and the Inheritance of Lactose Intolerance

    Lessons

    Students explore the genetic changes associated with lactose tolerance/intolerance and how the trait is inherited in families. Also available in Spanish.

  • West Nile Virus: Vectors and Hosts Game

    West Nile Virus: Vectors and Hosts Game

    Card Activities

    Play the West Nile virus game to learn how the virus spreads and how the outcome changes depending on the species that is infected. Resources are also available in Spanish.

  • Lizard Evolution Virtual Lab

    Lizard Evolution Virtual Lab

    Virtual Labs

    In the Lizard Evolution Virtual Lab students explore the evolution of the anole lizards in the Caribbean by collecting and analyzing their own data.  

  • Cancer and Cell Fate in the Intestinal Epithelium

    Cancer and Cell Fate in the Intestinal Epithelium

    Animations

    (2 min 17 sec) Disrupting the normal processes of differentiation and maturation of the intestinal epithelial cells can lead to cancer. Also available in Spanish.

  • Autism and the Structure and Function of Synapses

    Autism and the Structure and Function of Synapses

    Animations

    (2 min 3 sec) Genes associated with autism affect the structure and function of neuronal synapses.

  • Film Guides: The Origin of Tetrapods

    Film Guides: The Origin of Tetrapods

    Film Guides

    The following classroom-ready resources complement Great Transitions: The Origin of Tetrapods, which tells the story of the discovery of Tiktaalik, a creature with features common to fish and four-legged animals, or tetrapods.

  • Beaks As Tools: Selective Advantage in Changing Environments

    Beaks As Tools: Selective Advantage in Changing Environments

    Labs & Demos

    This classroom experiment supports the film The Origin of Species: The Beak of the Finch. Students collect and analyze data to learn why even slight variations in beak size can make the difference between life and death.

  • Explore Your Inner Animals

    Explore Your Inner Animals

    Click & Learn

    This interactive explores different anatomical features of the human body and what they reveal about the evolutionary history we share with other organisms, including earlier, long-extinct species.

  • Anole Lizards: An Example of Speciation

    Anole Lizards: An Example of Speciation

    Animations

    (2 min 38 sec) This animation features the anole lizards as an example of how a single species can split and multiply into many different species with distinct traits.

  • Film Guides: The Origin of Species: Lizards in an Evolutionary Tree

    Film Guides: The Origin of Species: Lizards in an Evolutionary Tree

    Film Guides

    The following classroom-ready resources complement The Origin of Species: Lizards in an Evolutionary Tree. Research on the anole lizards is enriching our understanding of evolutionary processes, such as adaptation by natural selection, convergent evolution, and the formation of new species. Also available in Spanish.

  • Film Guides: The Origin of Species: The Beak of the Finch

    Film Guides: The Origin of Species: The Beak of the Finch

    Film Guides

    The following classroom-ready resources complement The Origin of Species: The Beak of the Finch. By following four decades of research on the finches of the Galápagos islands, the film illustrates how geography and ecology can drive the evolution of new species.

  • Lactose Intolerance: Fact or Fiction

    Lactose Intolerance: Fact or Fiction

    Lessons

    Students evaluate and discuss several statements about lactose intolerance and evolution before and after watching the film. Also available in Spanish.

  • The Origin of Species: Lizards in an Evolutionary Tree

    The Origin of Species: Lizards in an Evolutionary Tree

    Short Films

    (17 min 45 sec) In the Caribbean islands, adaptation to several common habitats has led to a large adaptive radiation with interesting examples of convergent evolution. Also available in Spanish.

  • The Origin of Species: The Beak of the Finch

    The Origin of Species: The Beak of the Finch

    Short Films

    (15 min 54 sec) Four decades of research on finch species that live only on the Galápagos Islands illuminate how species form and multiply. Also available in Spanish.

  • Lactose Digestion in Infants

    Lactose Digestion in Infants

    Animations

    (53 sec) The lactase enzyme is produced in the small intestine of infants. It digests lactose by breaking it into glucose and galactose.

  • Diet and the Evolution of Salivary Amylase

    Diet and the Evolution of Salivary Amylase

    Lessons

    Students explore the effects of different diets on the evolution of an enzyme that breaks down starch. Also available in Spanish.

  • How Novel Icefish Genes Can Improve Human Health

    How Novel Icefish Genes Can Improve Human Health

    Lessons

    A lesson that requires students to read detailed scientific passages and explain how an understanding of specific icefish adaptations might lead to a treatment or cure for human disorders, such as osteoporosis and anemia. 

  • Icefish Blood Adaptations: Viscosity

    Icefish Blood Adaptations: Viscosity

    Lessons

    In this simple lab activity, students simulate and compare how blood pumps through the circulatory system of icefish and other fish.

  • Icefish Blood Adaptations: Antifreeze Proteins

    Icefish Blood Adaptations: Antifreeze Proteins

    Labs & Demos

    In this activity, students investigate the importance of antifreeze proteins for icefish survival through two simple labs.

  • Film Guides: The Birth and Death of Genes

    Film Guides: The Birth and Death of Genes

    Film Guides

    The following classroom-ready resources complement The Making of the Fittest: The Birth and Death of Genes, which describes how scientists have pieced together the evolutionary history of the Antarctic icefish. The icefish makes an excellent case study for genetic evolution as both the gain and loss of genes have led to key adaptations.

  • Molecular Genetics of Color Mutations in Rock Pocket Mice

    Molecular Genetics of Color Mutations in Rock Pocket Mice

    Lessons

    A lesson that requires students to transcribe and translate portions of the wild-type and mutant rock pocket mouse Mc1r genes and compare sequences to identify the locations and types of mutations responsible for the coat color variation described in the film. Also available in Spanish.

  • Battling Vector-Borne Diseases: Factors That Affect the Mosquito Life Cycle

    Battling Vector-Borne Diseases: Factors That Affect the Mosquito Life Cycle

    Labs & Demos

    In this activity, students rear mosquitoes in chambers and test variables that might affect the life cycle of the mosquito. Resources are also available in Spanish.

  • The Mosquito Life Cycle Activity

    The Mosquito Life Cycle Activity

    Lessons

    Students breed and observe mosquitoes in order to study their life cycle and demonstrate the utility of this data for public policy. Resources are also available in Spanish.

  • Motor cabal toxins block motor neuron synapses

    Motor cabal toxins block motor neuron synapses

    Animations

    (3 min 28 sec) Multiple cone snail toxins attack different molecules of the nervous system and cause paralysis.

  • Prialt blocks motor synapse in fish

    Prialt blocks motor synapse in fish

    Animations

    (2 min 31 sec) Prialt, a drug derived from cone snail venom, paralyzes fish by blocking calcium channels at a motor synapse.

  • Molecular Mechanism of Synaptic Function

    Molecular Mechanism of Synaptic Function

    Animations

    (1 min 9 sec) Electrical and chemical signals are used by neurons to communicate with one another at contact points called synapses. Also available in Spanish.

  • Signal molecules trigger transcription factors

    Signal molecules trigger transcription factors

    Animations

    (2 min 4 sec) Varying concentrations of a signaling molecule activate different transcription factors and determine cell fate.

  • Cells of the Immune System

    Cells of the Immune System

    Click & Learn

    An overview of the immune system, concentrating on the roles played by B and T lymphocytes, and the antigen-presentation system.

  • CTL killing a target cell

    CTL killing a target cell

    Clips

    (1 min 17 sec) Video microscopy of a cytotoxic T lymphocyte in action.

  • Planarian Regeneration and Stem Cells

    Planarian Regeneration and Stem Cells

    Scientists at Work

    (11 min 47 sec) A mini-documentary discussing the remarkable regenerative capabilities of the planarian, and how HHMI researcher Alejandro Sánchez Alvarado uses them to study the biology of stem cells.

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