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  • Using DNA to Explore Lizard Phylogeny

    Using DNA to Explore Lizard Phylogeny

    Activity

    This activity supports the film The Origin of Species: Lizards in an Evolutionary Tree. Students are guided to sort the lizard species by appearance, then generate a phylogenetic tree using the lizards’ DNA sequences to evaluate whether species that appear similar are closely related to each other.

  • Creating Phylogenetic Trees from DNA Sequences

    Creating Phylogenetic Trees from DNA Sequences

    Click & Learn

    This Click and Learn explains how DNA sequences can be used to generate such trees, and how to interpret them. English version is ADA accessible.

  • DNA Sequence Assembly

    DNA Sequence Assembly

    Click & Learn

    Learn the principles of how DNA is sequenced and assembled into whole genomes using the Sanger method, shotgun sequencing, or ultra-deep sequencing.

  • The Virus Hunter's Toolkit

    The Virus Hunter's Toolkit

    Lecture

    (58 min 33 sec) New technologies like the Virochip harness DNA's properties to identify and fight new viruses.

  • Viral Outbreak: The Science of Emerging Disease

    Viral Outbreak: The Science of Emerging Disease

    Lecture

    Watch two leading virus researchers explain how they use both simple and sophisticated technologies to detect and fight infectious agents.

  • Shotgun sequencing

    Shotgun sequencing

    Animation

    (1 min) In shotgun sequencing many copies of the entire genome are "blown up" into millions of small fragments. Each small fragment is sequenced. Powerful computers then assemble the individual fragments into the original configuration. Repeat sequences pose a problem for this approach because their sizes can be much larger than the small fragments.

  • Human genome sequencing

    Human genome sequencing

    Animation

    (1 min 49 sec) The public Human Genome Project started by identifying unique marker sequences distributed throughout the genome. Then, many copies of a small section of DNA were randomly cleaved into smaller fragments, and each small fragment was sequenced. Because there were originally many copies of the DNA in question, many fragments represented the same part of the genome. These were aligned by identifying overlapping regions of the sequence, and then they were assembled into the original DNA.

  • Bacterial Identification Virtual Lab

    Bacterial Identification Virtual Lab

    Virtual Lab

    This virtual lab will familiarize you with the science and techniques used to identify different types of bacteria based on their DNA sequences.