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Showing 21-26 of 26 Resources
  • Leading-Edge Bioinformatics

    Leading-Edge Bioinformatics

    Clip

    (6 min 36 sec) Peter Skewes-Cox, and Dr. Graham Ruby, both in the DeRisi lab, explain state-of-the-art DNA sequencing and bioinformatic technologies.

  • Shotgun sequencing

    Shotgun sequencing

    Animation

    (1 min) In shotgun sequencing many copies of the entire genome are "blown up" into millions of small fragments. Each small fragment is sequenced. Powerful computers then assemble the individual fragments into the original configuration. Repeat sequences pose a problem for this approach because their sizes can be much larger than the small fragments.

  • Human genome sequencing

    Human genome sequencing

    Animation

    (1 min 49 sec) The public Human Genome Project started by identifying unique marker sequences distributed throughout the genome. Then, many copies of a small section of DNA were randomly cleaved into smaller fragments, and each small fragment was sequenced. Because there were originally many copies of the DNA in question, many fragments represented the same part of the genome. These were aligned by identifying overlapping regions of the sequence, and then they were assembled into the original DNA.

  • Using DNA to Trace Human Migration

    Using DNA to Trace Human Migration

    Click & Learn

    All living humans originated from populations of ancestors who migrated out of Africa less than 100,000 years ago. Learn how scientists have used genetic markers to trace the migration routes and origins of modern human populations.

  • How to Analyze DNA Microarray Data

    How to Analyze DNA Microarray Data

    Click & Learn

    DNA microarrays, or gene chips, are an important new technology for genomic research. Learn how researchers use computing to analyze and interpret the huge datasets generated by microarray experiments.

  • Scanning Life's Matrix: Genes, Proteins, and Small Molecules

    Scanning Life's Matrix: Genes, Proteins, and Small Molecules

    Lecture

    In four presentations, Stuart L. Schreiber, PhD, and Eric S. Lander, PhD, open a window onto the fast-paced world of genomic science and chemical genetics.

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